SIM2 Antikörper (Middle Region)
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- Target Alle SIM2 Antikörper anzeigen
- SIM2 (Single-Minded Homolog 2 (SIM2))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Kaninchen, Hund, Meerschweinchen, Pferd, Rind (Kuh), Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SIM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- VLTEIEYKEL QLSLEQVSTA KSQDSWRTAL STSQETRKLV KPKNTKMKTK
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 91%, Pig: 93%, Rabbit: 92%, Rat: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SIM2. It was validated on Western Blot.
- Aufreinigung
- Affinity purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human SIM2
- Top Product
- Discover our top product SIM2 Primärantikörper
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- SIM2 (Single-Minded Homolog 2 (SIM2))
- Andere Bezeichnung
- SIM2 (SIM2 Produkte)
- Synonyme
- Xsim2 antikoerper, sim2-A antikoerper, xSim antikoerper, HMC13F06 antikoerper, HMC29C01 antikoerper, SIM antikoerper, bHLHe15 antikoerper, single-minded family bHLH transcription factor 2 S homeolog antikoerper, single-minded family bHLH transcription factor 2 antikoerper, single-minded homolog 2 (Drosophila) antikoerper, sim2.S antikoerper, sim2 antikoerper, SIM2 antikoerper, Sim2 antikoerper
- Hintergrund
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This gene represents a homolog of the Drosophila single-minded (sim) gene, which encodes a transcription factor that is a master regulator of neurogenesis. The encoded protein is ubiquitinated by RING-IBR-RING-type E3 ubiquitin ligases, including the parkin RBR E3 ubiquitin protein ligase. This gene maps within the so-called Down syndrome chromosomal region, and is thus thought to contribute to some specific Down syndrome phenotypes. Alternative splicing of this gene results in multiple transcript variants.
Alias Symbols: SIM2, BHLHE15,
Protein Size: 667 - Gen-ID
- 6493
- UniProt
- Q14190
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