PARPBP Antikörper (C-Term)

Produktnummer ABIN5517677

Produktdetails anti-PARPBP Antikörper

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PARPBP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: NEPPQHKNAK IPKKSNDSQN RLYGKLAKVA KSNKCTAKDK LISGQAKLTQ

Produktmerkmale: This is a rabbit polyclonal antibody against PARPBP. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human PARPBP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PARPBP

Target: PARPBP (PARP1 Binding Protein (PARPBP))

Andere Bezeichnung: PARPBP (PARPBP Produkte)

Synonyme: C12orf48 antikoerper, PARI antikoerper, PARPBP antikoerper, AROM antikoerper, C5H12orf48 antikoerper, PARP1BP antikoerper, si:ch211-260p3.2 antikoerper, zgc:136263 antikoerper, c12orf48 antikoerper, 4930547N16Rik antikoerper, AI503644 antikoerper, PARP1 binding protein antikoerper, PARP1 binding protein L homeolog antikoerper, PARPBP antikoerper, Parpbp antikoerper, parpbp antikoerper, parpbp.L antikoerper

Hintergrund: PARPBP is required to suppress inappropriate homologous recombination, thereby playing a central role DNA repair and in the maintenance of genomic stability. It antagonizes homologous recombination by interfering with the formation of the RAD51-DNA homologous recombination structure. It binds single-strand DNA and poly(A) homopolymers. It positively regulate the poly(ADP- ribosyl)ation activity of PARP1, however such function may be indirect.

Alias Symbols: PARPBP, C12orf48, PARI,

Protein Interaction Partner: UBC,

Protein Size: 294

Gen-ID: 55010