RNPS1 Antikörper (N-Term)

Produktnummer ABIN5517572

Produktdetails anti-RNPS1 Antikörper

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RNPS1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PTKRKDRSDE KSKDRSKDKG ATKESSEKDR GRDKTRKRRS ASSGSSSTRS

Produktmerkmale: This is a rabbit polyclonal antibody against RNPS1. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human RNPS1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu RNPS1

Target: RNPS1 (RNA-Binding Protein S1 (RNPS1))

Andere Bezeichnung: RNPS1 (RNPS1 Produkte)

Synonyme: E5.1 antikoerper, ribonucleic acid binding protein S1 antikoerper, RNA binding protein with serine rich domain 1 antikoerper, RNA binding protein S1, serine-rich domain antikoerper, Rnps1 antikoerper, RNPS1 antikoerper

Hintergrund: This gene encodes a protein that is part of a post-splicing multiprotein complex involved in both mRNA nuclear export and mRNA surveillance. mRNA surveillance detects exported mRNAs with truncated open reading frames and initiates nonsense-mediated mRNA decay (NMD). When translation ends upstream from the last exon-exon junction, this triggers NMD to degrade mRNAs containing premature stop codons. This protein binds to the mRNA and remains bound after nuclear export, acting as a nucleocytoplasmic shuttling protein. This protein contains many serine residues. Several transcript variants encoding different isoforms have been found for this gene.

Alias Symbols: RNPS1, LDC2,

Protein Interaction Partner: CLK2, HEXIM2, TRIM41, SDCBP2, ZNF473, U2AF1, SRPK2, ZBTB14, UBC, SUZ12, RNF2, BMI1, PIN1, SRPK1, UPF2, CSNK2A2, LUC7L3, TRA2A, ACIN1, TAF2, SRP54, TRA2B, SRSF4, SRSF1, PNN, Dlg4, PRPF38A, CHERP, EIF4A3, MAGOH, WIBG, UPF3B, SMU1, PRPF19, GNL3, RALY, SAP18,

Protein Size: 305

Gen-ID: 10921

NCBI Accession: XP_005255106

UniProt: Q15287