Nyctalopin Antikörper (Middle Region)

Produktnummer ABIN5517443

Produktdetails anti-Nyctalopin Antikörper

Target: Nyctalopin (NYX)

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nyctalopin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GSGRVTDVPC ASPGSVAGLD LSQVTFGRSS DGLCVDPEEL NLTTSSPGPS

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NYX

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu Nyctalopin

Target: Nyctalopin (NYX)

Andere Bezeichnung: NYX (NYX Produkte)

Synonyme: MGC84276 antikoerper, CLRP antikoerper, CSNB1 antikoerper, CSNB1A antikoerper, CSNB4 antikoerper, NBM1 antikoerper, CLNP antikoerper, nob antikoerper, RGD1561300 antikoerper, nyctalopin antikoerper, nyctalopin L homeolog antikoerper, uncharacterized LOC491837 antikoerper, NYX antikoerper, nyx.L antikoerper, LOC491837 antikoerper, nyx antikoerper, Nyx antikoerper

Hintergrund: The product of this gene belongs to the small leucine-rich proteoglycan (SLRP) family of proteins. Defects in this gene are the cause of congenital stationary night blindness type 1 (CSNB1), also called X-linked congenital stationary night blindness (XLCSNB). CSNB1 is a rare inherited retinal disorder characterized by impaired scotopic vision, myopia, hyperopia, nystagmus and reduced visual acuity. The role of other SLRP proteins suggests that mutations in this gene disrupt developing retinal interconnections involving the ON-bipolar cells, leading to the visual losses seen in patients with complete CSNB.

Alias Symbols: CLRP, NBM1, CSNB1, CSNB4, CSNB1A

Protein Size: 481

Gen-ID: 60506

NCBI Accession: NM_022567, NP_072089

UniProt: Q9GZU5