TIFA Antikörper (Middle Region)

Produktnummer ABIN5517365

Produktdetails anti-TIFA Antikörper

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TIFA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FGRNSNICHY TFQDKQVSRV QFSLQLFKKF NSSVLSFEIK NMSKKTNLIV

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TIFA

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TIFA

Target: TIFA (TRAF-Interacting Protein with Forkhead-Associated Domain (TIFA))

Andere Bezeichnung: TIFA (TIFA Produkte)

Synonyme: TIFA antikoerper, xtifa antikoerper, T2BP antikoerper, T6BP antikoerper, TIFAA antikoerper, T2bp antikoerper, Ab2-389 antikoerper, TRAF interacting protein with forkhead associated domain antikoerper, TRAF-interacting protein with forkhead-associated domain antikoerper, TRAF-interacting protein with forkhead-associated domain S homeolog antikoerper, TIFA antikoerper, tifa antikoerper, Tifa antikoerper, tifa.S antikoerper

Hintergrund: Adapter protein which mediates the IRAK1 and TRAF6 interaction following IL-1 stimulation, resulting in the downstream activation of NF-kappa-B and AP-1 pathways. Induces the oligomerization and polyubiquitination of TRAF6, which leads to the activation of TAK1 and IKK through a proteasome-independent mechanism.

Alias Symbols: T2BP, T6BP, TIFAA

Protein Size: 184

Gen-ID: 92610

NCBI Accession: NM_052864, NP_443096

UniProt: Q96CG3