GSTM4 Antikörper (Middle Region)

Produktnummer ABIN5516880

Produktdetails anti-GSTM4 Antikörper

Target: GSTM4 (Glutathione S-Transferase mu 4 (GSTM4))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GSTM4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: EYTDSSYEEK KYTMGDAPDY DRSQWLNEKF KLGLDFPNLP YLIDGAHKIT

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human GSTM4

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu GSTM4

Target: GSTM4 (Glutathione S-Transferase mu 4 (GSTM4))

Andere Bezeichnung: GSTM4 (GSTM4 Produkte)

Synonyme: GSTM4-4 antikoerper, GTM4 antikoerper, 1110004G14Rik antikoerper, GSTM7-7 antikoerper, Gstb-4 antikoerper, Gstb4 antikoerper, glutathione S-transferase mu 4 antikoerper, glutathione S-transferase, mu 4 antikoerper, GSTM4 antikoerper, Gstm4 antikoerper

Hintergrund: Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Multiple transcript variants, each encoding a distinct protein isoform, have been identified.

Alias Symbols: GTM4, GSTM4-4,

Protein Size: 218

Gen-ID: 2948

NCBI Accession: NM_000850, NP_000841

UniProt: Q03013