MR1 Antikörper (N-Term)

Produktnummer ABIN5516858

Produktdetails anti-MR1 Antikörper

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RTHSLRYFRL GVSDPIHGVP EFISVGYVDS HPITTYDSVT RQKEPRAPWM

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human MR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu MR1

Target: MR1 (Major Histocompatibility Complex, Class I-Related (MR1))

Andere Bezeichnung: MR1 (MR1 Produkte)

Synonyme: YFV antikoerper, hlals antikoerper, MGC154362 antikoerper, MR1 antikoerper, DKFZp468C1823 antikoerper, HLALS antikoerper, H2ls antikoerper, Hlals antikoerper, MHC class I antigen YF5 antikoerper, major histocompatibility complex, class I-related antikoerper, major histocompatibility complex, class I-related L homeolog antikoerper, YF5 antikoerper, MR1 antikoerper, mr1.L antikoerper, mr1 antikoerper, Mr1 antikoerper

Hintergrund: MAIT (mucosal-associated invariant T-cells) lymphocytes represent a small population of T-cells primarily found in the gut. The protein encoded by this gene is an antigen-presenting molecule that presents metabolites of microbial vitamin B to MAITs. This presentation may activate the MAITs to regulate the amounts of specific types of bacteria in the gut. Several transcript variants encoding different isoforms have been found for this gene, and a pseudogene of it has been detected about 36 kbp upstream on the same chromosome.

Alias Symbols: HLALS

Protein Size: 296

Gen-ID: 3140

NCBI Accession: NM_001194999, NP_001181928

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints