SUN2 Antikörper (N-Term)

Produktnummer ABIN5516851

Produktdetails anti-SUN2 Antikörper

Target: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SUN2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RSQRLTRYSQ GDDDGSSSSG GSSVAGSQST LFKDSPLRTL KRKSSNMKRL

Produktmerkmale: This is a rabbit polyclonal antibody against SUN2. It was validated on Western Blot.

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Human SUN2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu SUN2

Target: SUN2 (Sad1 and UNC84 Domain Containing 2 (SUN2))

Andere Bezeichnung: SUN2 (SUN2 Produkte)

Synonyme: UNC84B antikoerper, B230369L08Rik antikoerper, C030011B15 antikoerper, Unc84b antikoerper, RGD1563141 antikoerper, Sad1 and UNC84 domain containing 2 antikoerper, SUN2 antikoerper, Sun2 antikoerper

Hintergrund: SUN1 (MIM 607723) and SUN2 are inner nuclear membrane (INM) proteins that play a major role in nuclear-cytoplasmic connection by formation of a 'bridge' across the nuclear envelope, known as the LINC complex, via interaction with the conserved luminal KASH domain of nesprins (e.g., SYNE1, MIM 608441) located in the outer nuclear membrane (ONM). The LINC complex provides a direct connection between the nuclear lamina and the cytoskeleton, which contributes to nuclear positioning and cellular rigidity.

Alias Symbols: SUN2, FRIGG, KIAA0668, RAB5IP, UNC84B,

Protein Interaction Partner: FBXW11, NRM, BTRC, UBC, WHSC1, RPS20, RAB5B, RAB5A, TP53BP1, C9orf3, SYNE1, SYNE2, AGO3, USP20, HGS, RAB5C,

Protein Size: 717

Gen-ID: 25777

NCBI Accession: XP_005261558

UniProt: Q9UH99

Pathways: Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom, Phosphorylierungen bei SARS-CoV-2 Infektion