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TYROBP Antikörper (Middle Region)

TYROBP Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5515952
  • Target Alle TYROBP Antikörper anzeigen
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Bindungsspezifität
    • 16
    • 15
    • 15
    • 11
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reaktivität
    • 49
    • 20
    • 4
    Human
    Wirt
    • 66
    • 1
    • 1
    Kaninchen
    Klonalität
    • 59
    • 9
    Polyklonal
    Konjugat
    • 22
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    Dieser TYROBP Antikörper ist unkonjugiert
    Applikation
    • 41
    • 30
    • 26
    • 26
    • 21
    • 18
    • 12
    • 6
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    IALAVYFLGR LVPRGRGAAE AATRKQRITE TESPYQELQG QRSDVYSDLN
    Aufreinigung
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human TYROBP
    Top Product
    Discover our top product TYROBP Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 23 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    TYROBP (TYRO Protein tyrosine Kinase Binding Protein (TYROBP))
    Andere Bezeichnung
    TYROBP (TYROBP Produkte)
    Synonyme
    TYROBP antikoerper, DAP12 antikoerper, tyrpbp antikoerper, Karap antikoerper, KARAP antikoerper, PLOSL antikoerper, Ly83 antikoerper, dap12 antikoerper, TYRO protein tyrosine kinase binding protein antikoerper, Tyro protein tyrosine kinase binding protein antikoerper, TYROBP antikoerper, tyrobp antikoerper, Tyrobp antikoerper
    Hintergrund
    This gene encodes a transmembrane signaling polypeptide which contains an immunoreceptor tyrosine-based activation motif (ITAM) in its cytoplasmic domain. The encoded protein may associate with the killer-cell inhibitory receptor (KIR) family of membrane glycoproteins and may act as an activating signal transduction element. This protein may bind zeta-chain (TCR) associated protein kinase 70 kDa (ZAP-70) and spleen tyrosine kinase (SYK) and play a role in signal transduction, bone modeling, brain myelination, and inflammation. Mutations within this gene have been associated with polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL), also known as Nasu-Hakola disease. Its putative receptor, triggering receptor expressed on myeloid cells 2 (TREM2), also causes PLOSL. Multiple alternative transcript variants encoding distinct isoforms have been identified for this gene.

    Alias Symbols: DAP12, KARAP, PLOSL

    Protein Size: 144
    Gen-ID
    7305
    NCBI Accession
    NP_001166985
    UniProt
    K7ES93
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