DUSP2 Antikörper (C-Term)

Produktnummer ABIN5515662

Produktdetails anti-DUSP2 Antikörper

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DUSP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: SATICLAYLM QSRRVRLDEA FDFVKQRRGV ISPNFSFMGQ LLQFETQVLC

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human DUSP2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DUSP2

Target: DUSP2 (Dual Specificity Phosphatase 2 (DUSP2))

Andere Bezeichnung: DUSP2 (DUSP2 Produkte)

Synonyme: zgc:91929 antikoerper, wu:fj40g04 antikoerper, PAC-1 antikoerper, PAC1 antikoerper, dual specificity phosphatase 2 antikoerper, dusp2 antikoerper, DUSP2 antikoerper, Dusp2 antikoerper

Hintergrund: The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus.

Alias Symbols: PAC1, PAC-1

Protein Size: 314

Gen-ID: 1844

NCBI Accession: NM_004418, NP_004409

UniProt: Q05923