ASIP Antikörper (Middle Region)

Produktnummer ABIN5515388

Produktdetails anti-ASIP Antikörper

Target: ASIP (Agouti Signaling Protein (ASIP))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASIP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CFFTANSHLP PEEKLRDDRS LRSNSSVNLL DVPSVSIVAL NKKSKQIGRK

Aufreinigung: Affinity purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human ASIP

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu ASIP

Target: ASIP (Agouti Signaling Protein (ASIP))

Andere Bezeichnung: ASIP (ASIP Produkte)

Synonyme: AGSW antikoerper, AGTI antikoerper, AGTIL antikoerper, ASP antikoerper, SHEP9 antikoerper, ASIP antikoerper, AA960621 antikoerper, AI256638 antikoerper, D8Ertd580e antikoerper, PAR-3 antikoerper, Par3 antikoerper, Pard3a antikoerper, agouti signaling protein antikoerper, par-3 family cell polarity regulator antikoerper, ASIP antikoerper, Asip antikoerper, asip antikoerper, Pard3 antikoerper

Hintergrund: In mice, the agouti gene encodes a paracrine signaling molecule that causes hair follicle melanocytes to synthesize pheomelanin, a yellow pigment, instead of the black or brown pigment, eumelanin. Pleiotropic effects of constitutive expression of the mouse gene include adult-onset obesity, increased tumor susceptibility, and premature infertility. This gene is highly similar to the mouse gene and encodes a secreted protein that may (1) affect the quality of hair pigmentation, (2) act as a pharmacological antagonist of alpha-melanocyte-stimulating hormone, (3) play a role in neuroendocrine aspects of melanocortin action, and (4) have a functional role in regulating lipid metabolism in adipocytes.

Alias Symbols: ASP, AGSW, AGTI, AGTIL, SHEP9

Protein Size: 132

Gen-ID: 434

NCBI Accession: NM_001672, NP_001663

UniProt: P42127

Pathways: Cell-Cell Junction Organization, Feeding Behaviour