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APEX2 Antikörper (C-Term)

APEX2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN5515372
  • Target Alle APEX2 Antikörper anzeigen
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 20
    • 16
    • 15
    Human
    Wirt
    • 34
    • 2
    Kaninchen
    Klonalität
    • 36
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser APEX2 Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 15
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    Sequenz
    LMTPKTPEEK AVAKVVKGQA KTSEAKDEKE LRTSFWKSVL AGPLRTPLCG
    Homologie
    Cow: 85%, Horse: 93%, Human: 100%, Rat: 77%
    Aufreinigung
    Affinity purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the C terminal region of human APEX2
    Top Product
    Discover our top product APEX2 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    APEX2 (APEX Nuclease (Apurinic/apyrimidinic Endonuclease) 2 (APEX2))
    Andere Bezeichnung
    APEX2 (APEX2 Produkte)
    Synonyme
    APE2 antikoerper, APEXL2 antikoerper, XTH2 antikoerper, ape2 antikoerper, apexl2 antikoerper, xth2 antikoerper, zgc:55889 antikoerper, C430040P13Rik antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 2 antikoerper, APEX nuclease (apurinic/apyrimidinic endonuclease) 2 antikoerper, apurinic/apyrimidinic endodeoxyribonuclease 2 L homeolog antikoerper, apurinic/apyrimidinic endonuclease 2 antikoerper, APEX2 antikoerper, apex2 antikoerper, apex2.L antikoerper, Apex2 antikoerper
    Hintergrund
    Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

    Alias Symbols: APE2, XTH2, ZGRF2, APEXL2

    Protein Interaction Partner: UBC, PDE12, APP, NEDD4L, CCDC85B, NINL, HOOK2, PGR, CALCOCO2, TRIM37, EFEMP2, TRAF2, PCNA,

    Protein Size: 518
    Gen-ID
    27301
    NCBI Accession
    NM_014481, NP_055296
    UniProt
    Q9UBZ4
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