DEDD Antikörper (Middle Region)

Produktnummer ABIN5515285

Produktdetails anti-DEDD Antikörper

Target: DEDD (Death Effector Domain Containing (DEDD))

Bindungsspezifität: Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEDD Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PTSGPQMCSK RPARGRATLG SQRKRRKSVT PDPKEKQTCD IRLRVRAEYC

Produktmerkmale: This is a rabbit polyclonal antibody against DEDD. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human DEDD

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu DEDD

Target: DEDD (Death Effector Domain Containing (DEDD))

Andere Bezeichnung: DEDD (DEDD Produkte)

Synonyme: CASP8IP1 antikoerper, DEDD1 antikoerper, DEFT antikoerper, FLDED1 antikoerper, Dedpro1 antikoerper, KE05 antikoerper, Deft antikoerper, death effector domain containing antikoerper, death effector domain-containing antikoerper, DEDD antikoerper, Dedd antikoerper

Hintergrund: This gene encodes a protein that contains a death effector domain (DED). DED is a protein-protein interaction domain shared by adaptors, regulators and executors of the programmed cell death pathway. Overexpression of this gene was shown to induce weak apoptosis. Upon stimulation, this protein was found to translocate from cytoplasm to nucleus and colocalize with UBTF, a basal factor required for RNA polymerase I transcription, in the nucleolus. At least three transcript variants encoding the same protein have been found for this gene.

Alias Symbols: DEDD, DEDPRO1, DEFT, KE05,

Protein Interaction Partner: APLP2, SMAD3, BATF2, SHMT1, APP, UBC, HOXD4, USP22, DEDD2, GTF3C1, CFLAR, FADD, CASP8, CASP10, CASP3, KRT18, KRT8, GTF3C3, DEDD, CCDC59, RANBP3, KHK,

Protein Size: 318

Gen-ID: 9191

NCBI Accession: NP_127491

UniProt: O75618