ASK1 Antikörper (pSer83)

Produktnummer ABIN550447

Produktdetails anti-ASK1 Antikörper

Target: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Bindungsspezifität: pSer83

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ASK1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphpeptide of MAP3K5.

Spezifität: This phospho specific polyclonal antibody reacts human pS83 ASK1.

Kreuzreaktivität: Human, Maus

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S83 of human MAP3K5.

Anwendungsinformationen

Applikationshinweise: ELISA (1:5000-1:10000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In 20 mM KH₂PO₄, 150 mM NaCl, pH 7.2 (0.01 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ASK1 Antikörper (ABIN550447)

Zou, Tsutsui, Ray, Blomquist, Ichijo, Ucker, Kiyokawa: "The cell cycle-regulatory CDC25A phosphatase inhibits apoptosis signal-regulating kinase 1." in: Molecular and cellular biology, Vol. 21, Issue 14, pp. 4818-28, (2001) (PubMed).

Matsuzawa, Ichijo: "Molecular mechanisms of the decision between life and death: regulation of apoptosis by apoptosis signal-regulating kinase 1." in: Journal of biochemistry, Vol. 130, Issue 1, pp. 1-8, (2001) (PubMed).

Morita, Saitoh, Tobiume, Matsuura, Enomoto, Nishitoh, Ichijo: "Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress." in: The EMBO journal, Vol. 20, Issue 21, pp. 6028-36, (2001) (PubMed).

Details zu ASK1

Target: ASK1 (MAP3K5) (Mitogen-Activated Protein Kinase Kinase Kinase 5 (MAP3K5))

Andere Bezeichnung: MEKK5 / ASK1 (MAP3K5 Produkte)

Synonyme: ASK1 antikoerper, MAPKKK5 antikoerper, MEKK5 antikoerper, mitogen-activated protein kinase kinase kinase 5 antikoerper, MUD21.11 antikoerper, MUD21_11 antikoerper, 7420452D20Rik antikoerper, ASK antikoerper, Mekk5 antikoerper, Ask1 antikoerper, RGD1306565 antikoerper, mitogen-activated protein kinase kinase kinase 5 antikoerper, MAP3K5 antikoerper, MAPKKK5 antikoerper, Map3k5 antikoerper, map3k5 antikoerper

Gen-ID: 4217

Pathways: MAPK Signalweg, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response