NFAT1 Antikörper (pSer330)

Produktnummer ABIN548643

Produktdetails anti-NFAT1 Antikörper

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Bindungsspezifität: pSer330

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NFAT1 Antikörper ist unkonjugiert

Applikation: ELISA, Dot Blot (DB)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of NFATC2.

Kreuzreaktivität: Human

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S330 of human NFATC2.

Anwendungsinformationen

Applikationshinweise: ELISA (1:1000)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-NFAT1 Antikörper (ABIN548643)

Dong, Patino-Lopez, Candotti, Shaw: "Structure-function analysis of the WIP role in T cell receptor-stimulated NFAT activation: evidence that WIP-WASP dissociation is not required and that the WIP NH2 terminus is inhibitory." in: The Journal of biological chemistry, Vol. 282, Issue 41, pp. 30303-10, (2007) (PubMed).

Gibson, Hedgcock, Aufiero, Wilson, Hafner, Tsokos, Wong: "Induction of the CTLA-4 gene in human lymphocytes is dependent on NFAT binding the proximal promoter." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 179, Issue 6, pp. 3831-40, (2007) (PubMed).

Golks, Tran, Goetschy, Guerini: "Requirement for O-linked N-acetylglucosaminyltransferase in lymphocytes activation." in: The EMBO journal, Vol. 26, Issue 20, pp. 4368-79, (2007) (PubMed).

Details zu NFAT1

Target: NFAT1 (Nuclear Factor of Activated T-Cells, Cytoplasmic, Calcineurin-Dependent 2 (NFAT1))

Andere Bezeichnung: NFATC2 (NFAT1 Produkte)

Synonyme: NFATC2 antikoerper, AI607462 antikoerper, NF-ATc2 antikoerper, NFAT1 antikoerper, NFAT1-D antikoerper, Nfatp antikoerper, NFATP antikoerper, nuclear factor of activated T-cells 2 antikoerper, nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 antikoerper, NFATC2 antikoerper, nfatc2 antikoerper, Nfatc2 antikoerper

Gen-ID: 4773

Pathways: RTK Signalweg, WNT Signalweg, Fc-epsilon Rezeptor Signalübertragung, VEGF Signaling, BCR Signaling