BNIP3
Reaktivität: Human
WB, IF, ICC
Wirt: Kaninchen
Polyclonal
Biotin
Applikationshinweise
Western Blot (1-2 μg/mL) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (0.5-1 μg/mL) Immunohistochemistry (Frozen sections) (0.5-1 μg/mL) Immunocytochemistry (0.5-1 μg/mL) The optimal working dilution should be determine
This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Store at -20°C on dry atmosphere. After reconstitution with 200 uL of deionized water and concentration will be 500 ug/mL, store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Burton, Henson, Baijal, Eisenstat, Gibson: "The pro-cell death Bcl-2 family member, BNIP3, is localized to the nucleus of human glial cells: Implications for glioblastoma multiforme tumor cell survival under hypoxia." in: International journal of cancer. Journal international du cancer, Vol. 118, Issue 7, pp. 1660-9, (2006) (PubMed).
Ray, Chen, Vande Velde, Cizeau, Park, Reed, Gietz, Greenberg: "BNIP3 heterodimerizes with Bcl-2/Bcl-X(L) and induces cell death independent of a Bcl-2 homology 3 (BH3) domain at both mitochondrial and nonmitochondrial sites." in: The Journal of biological chemistry, Vol. 275, Issue 2, pp. 1439-48, (2000) (PubMed).
Target
BNIP3
(BCL2/adenovirus E1B 19kDa Interacting Protein 3 (BNIP3))