Integrin beta 4 Antikörper (ITGB4)

Details for Product anti-ITGB4 Antibody No. ABIN548463
Antigen
Reaktivität
Human
206
81
53
5
5
1
1
Wirt
Kaninchen
118
91
26
2
2
Klonalität
Polyklonal
Konjugat
Dieser Integrin beta 4 Antikörper ist unkonjugiert
13
12
5
5
5
5
5
5
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
154
108
88
61
53
38
33
30
21
13
10
9
2
2
2
1
1
1
Optionen
Verwendungszweck Rabbit polyclonal antibody raised against synthetic phosphopeptide of ITGB4.
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1526 of human ITGB4.
Spezifität This peptide sequence is found in all three integrin-b4 isoforms and is highly conserved in rat and mouse integrin-b4.
Kreuzreaktivität Maus, Ratte (Rattus)
Antigen
Andere Bezeichnung CD104 (ITGB4 Antibody Abstract)
Pathways Integrin Complex
Applikations-hinweise ELISA (1:2000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Buffer In PBS (50 % glycerol, 1 mg/mL BSA, 0.05 % sodium azide)
Lagerung -20 °C
Informationen zur Lagerung Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Image no. 1 for anti-Integrin beta 4 (ITGB4) antibody (ABIN548463) Western blot analysis of A-431 cells serum starved overnight (lane 1) and treated wit...
Produkt verwendet in: Shaw: "Identification of insulin receptor substrate 1 (IRS-1) and IRS-2 as signaling intermediates in the alpha6beta4 integrin-dependent activation of phosphoinositide 3-OH kinase and promotion of invasion." in: Molecular and cellular biology, Vol. 21, Issue 15, pp. 5082-93, 2001 (PubMed).

Dans, Gagnoux-Palacios, Blaikie, Klein, Mariotti, Giancotti: "Tyrosine phosphorylation of the beta 4 integrin cytoplasmic domain mediates Shc signaling to extracellular signal-regulated kinase and antagonizes formation of hemidesmosomes." in: The Journal of biological chemistry, Vol. 276, Issue 2, pp. 1494-502, 2001 (PubMed).