GCK Antikörper (C-Term)

Produktnummer ABIN544490

Produktdetails anti-GCK Antikörper

Target: GCK (Glucokinase (Hexokinase 4) (GCK))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of GCK.

Kreuzreaktivität: Human, Maus

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to C-terminus of human GCK.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:50-100)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-GCK Antikörper (ABIN544490)

Gloyn, Noordam, Willemsen, Ellard, Lam, Campbell, Midgley, Shiota, Buettger, Magnuson, Matschinsky, Hattersley: "Insights into the biochemical and genetic basis of glucokinase activation from naturally occurring hypoglycemia mutations." in: Diabetes, Vol. 52, Issue 9, pp. 2433-40, (2003) (PubMed).

Pruhova, Ek, Lebl, Sumnik, Saudek, Andel, Pedersen, Hansen: "Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha." in: Diabetologia, Vol. 46, Issue 2, pp. 291-5, (2003) (PubMed).

Rizzo, Magnuson, Drain, Piston: "A functional link between glucokinase binding to insulin granules and conformational alterations in response to glucose and insulin." in: The Journal of biological chemistry, Vol. 277, Issue 37, pp. 34168-75, (2002) (PubMed).

Details zu GCK

Target: GCK (Glucokinase (Hexokinase 4) (GCK))

Andere Bezeichnung: Glucokinase / Hexokinase-4 (GCK Produkte)

Synonyme: FGQTL3 antikoerper, GK antikoerper, GLK antikoerper, HHF3 antikoerper, HK4 antikoerper, HKIV antikoerper, HXKP antikoerper, LGLK antikoerper, MODY2 antikoerper, Gk antikoerper, Gls006 antikoerper, GCK antikoerper, BA4487 antikoerper, glk antikoerper, hk4 antikoerper, hhf3 antikoerper, hkiv antikoerper, hxkp antikoerper, gck-A antikoerper, mody2 antikoerper, glucokinase antikoerper, GLUKA antikoerper, RNGK2 antikoerper, glucokinase antikoerper, glucokinase (hexokinase 4) L homeolog antikoerper, glucokinase (hexokinase 4) antikoerper, GCK antikoerper, Gck antikoerper, glcK antikoerper, Bphyt_1025 antikoerper, Halhy_6548 antikoerper, gk antikoerper, gck.L antikoerper, gck antikoerper

Gen-ID: 2645

Pathways: MAPK Signalweg, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Cellular Glucan Metabolic Process, Regulation of Carbohydrate Metabolic Process