ICMT
Reaktivität: Human, Maus
WB, IF (cc), IF (p)
Wirt: Kaninchen
Polyclonal
Alexa Fluor 750
Applikationshinweise
Western Blot (1:1000) The optimal working dilution should be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In PBS (0.09 % sodium azide)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Bergo, Gavino, Hong, Beigneux, McMahon, Casey, Young: "Inactivation of Icmt inhibits transformation by oncogenic K-Ras and B-Raf." in: The Journal of clinical investigation, Vol. 113, Issue 4, pp. 539-50, (2004) (PubMed).
Van Dessel, De Busser, Lagrou: "Prenylcysteine carboxymethyltransferase type III activity is decreased in retinoic acid-treated SH-SY5Y neuroblastoma cells." in: The international journal of biochemistry & cell biology, Vol. 34, Issue 5, pp. 477-86, (2002) (PubMed).
Ahmad, Zhang, Zhang, Papharalambus, Alexander: "Role of isoprenylcysteine carboxyl methyltransferase in tumor necrosis factor-alpha stimulation of expression of vascular cell adhesion molecule-1 in endothelial cells." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 22, Issue 5, pp. 759-64, (2002) (PubMed).