MLL/KMT2A Antikörper (AA 312-343)

Produktnummer ABIN543317

Produktdetails anti-MLL/KMT2A Antikörper

Target: MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

Bindungsspezifität: AA 312-343

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MLL/KMT2A Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of MLL.

Kreuzreaktivität: Human

Immunogen: A synthetic peptide (conjugated with KLH) corresponding to amino acids 312-343 at C-terminus of human MLL.

Anwendungsinformationen

Applikationshinweise: Immunohistochemistry (1:10-50)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-MLL/KMT2A Antikörper (ABIN543317)

Pegram, Megonigal, Lange, Nowell, Rowley, Rappaport, Felix: "t(3;11) translocation in treatment-related acute myeloid leukemia fuses MLL with the GMPS (GUANOSINE 5' MONOPHOSPHATE SYNTHETASE) gene." in: Blood, Vol. 96, Issue 13, pp. 4360-2, (2000) (PubMed).

Sano, Hayakawa, Piao, Kosaka, Nakamura: "Novel SH3 protein encoded by the AF3p21 gene is fused to the mixed lineage leukemia protein in a therapy-related leukemia with t(3;11) (p21;q23)." in: Blood, Vol. 95, Issue 3, pp. 1066-8, (2000) (PubMed).

Megonigal, Cheung, Rappaport, Nowell, Wilson, Jones, Addya, Leonard, Kushner, Williams, Lange, Felix: "Detection of leukemia-associated MLL-GAS7 translocation early during chemotherapy with DNA topoisomerase II inhibitors." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, Issue 6, pp. 2814-9, (2000) (PubMed).

Details zu MLL/KMT2A

Target: MLL/KMT2A (MLL) (Myeloid/lymphoid Or Mixed-Lineage Leukemia (MLL))

Andere Bezeichnung: MLL / HRX (MLL Produkte)

Synonyme: ALL-1 antikoerper, CXXC7 antikoerper, HRX antikoerper, HTRX1 antikoerper, MLL antikoerper, MLL/GAS7 antikoerper, MLL1A antikoerper, TET1-MLL antikoerper, TRX1 antikoerper, WDSTS antikoerper, 6430520K01 antikoerper, All1 antikoerper, Cxxc7 antikoerper, Mll antikoerper, Mll1 antikoerper, mKIAA4050 antikoerper, lysine methyltransferase 2A antikoerper, lysine (K)-specific methyltransferase 2A antikoerper, KMT2A antikoerper, Kmt2a antikoerper

Gen-ID: 4297

Pathways: Warburg Effekt