ErbB2/Her2 Antikörper (pTyr1248)

Produktnummer ABIN542921

Produktdetails anti-ErbB2/Her2 Antikörper

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Bindungsspezifität: pTyr1248

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ErbB2/Her2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Dot Blot (DB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic phosphopeptide of ERBB2.

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Synthetic Peptide.

Immunogen: Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding Y1248 of human ERBB2.

Anwendungsinformationen

Applikationshinweise: Western Blot (1:8000)
Immunohistochemistry (1:50-1:100)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-ErbB2/Her2 Antikörper (ABIN542921)

Beckers, Herrmann, Rieger, Drobyshev, Horsch, Hrabé de Angelis, Seliger: "Identification and validation of novel ERBB2 (HER2, NEU) targets including genes involved in angiogenesis." in: International journal of cancer. Journal international du cancer, Vol. 114, Issue 4, pp. 590-7, (2005) (PubMed).

Provinciali, Re, Donnini, Orlando, Bartozzi, Di Stasio, Smorlesi: "Effect of resveratrol on the development of spontaneous mammary tumors in HER-2/neu transgenic mice." in: International journal of cancer. Journal international du cancer, Vol. 115, Issue 1, pp. 36-45, (2005) (PubMed).

Yee, Young, Rosol, Vanbuskirk, Clinton: "Dietary (n-3) polyunsaturated fatty acids inhibit HER-2/neu-induced breast cancer in mice independently of the PPARgamma ligand rosiglitazone." in: The Journal of nutrition, Vol. 135, Issue 5, pp. 983-8, (2005) (PubMed).

Details zu ErbB2/Her2

Target: ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))

Andere Bezeichnung: CD340 / ERBB2 / HER2 (ErbB2/Her2 Produkte)

Synonyme: CD340 antikoerper, HER-2 antikoerper, HER-2/neu antikoerper, HER2 antikoerper, MLN 19 antikoerper, NEU antikoerper, NGL antikoerper, TKR1 antikoerper, Erbb-2 antikoerper, Neu antikoerper, c-erbB2 antikoerper, c-neu antikoerper, mKIAA3023 antikoerper, wu:fv70f10 antikoerper, zgc:63601 antikoerper, erb2 antikoerper, erb-b2 receptor tyrosine kinase 2 antikoerper, ERBB2 antikoerper, Erbb2 antikoerper, erbb2 antikoerper

Gen-ID: 2064

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Skeletal Muscle Fiber Development