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NEDD8 Antikörper (N-Term)

NEDD8 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN542757
  • Target Alle NEDD8 Antikörper anzeigen
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Bindungsspezifität
    • 15
    • 13
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 67
    • 29
    • 25
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 64
    • 4
    • 4
    Kaninchen
    Klonalität
    • 60
    • 12
    Polyklonal
    Konjugat
    • 31
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NEDD8 Antikörper ist unkonjugiert
    Applikation
    • 39
    • 27
    • 27
    • 13
    • 13
    • 13
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit polyclonal antibody raised against synthetic peptide of NEDD8.
    Kreuzreaktivität
    Human
    Immunogen
    A synthetic peptide (conjugated with KLH) corresponding to N-terminus of human NEDD8.
    Top Product
    Discover our top product NEDD8 Primärantikörper
  • Applikationshinweise
    Western Blot (1:1000)
    Immunohistochemistry (1:50-100)
    The optimal working dilution should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In PBS (0.09 % sodium azide)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Fan, Bigsby, Nephew et al.: "The NEDD8 pathway is required for proteasome-mediated degradation of human estrogen receptor (ER)-alpha and essential for the antiproliferative activity of ICI 182,780 in ERalpha-positive breast ..." in: Molecular endocrinology (Baltimore, Md.), Vol. 17, Issue 3, pp. 356-65, (2003) (PubMed).

    Bohnsack, Haas: "Conservation in the mechanism of Nedd8 activation by the human AppBp1-Uba3 heterodimer." in: The Journal of biological chemistry, Vol. 278, Issue 29, pp. 26823-30, (2003) (PubMed).

    Wu, Yamoah, Dolios, Gan-Erdene, Tan, Chen, Lee, Wei, Wilkinson, Wang, Pan: "DEN1 is a dual function protease capable of processing the C terminus of Nedd8 and deconjugating hyper-neddylated CUL1." in: The Journal of biological chemistry, Vol. 278, Issue 31, pp. 28882-91, (2003) (PubMed).

  • Target
    NEDD8 (Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8))
    Andere Bezeichnung
    NEDD8 (NEDD8 Produkte)
    Synonyme
    NEDD-8 antikoerper, Rub1 antikoerper, CG10679 antikoerper, Dmel\\CG10679 antikoerper, NEDD8 antikoerper, dNEDD8 antikoerper, nedd8 antikoerper, ubiquitin antikoerper, si:zc14a17.5 antikoerper, GB17785 antikoerper, DDBDRAFT_0218116 antikoerper, DDBDRAFT_0238041 antikoerper, DDB_0218116 antikoerper, DDB_0238041 antikoerper, nedd8.S antikoerper, neural precursor cell expressed, developmentally down-regulated 8 antikoerper, neural precursor cell expressed, developmentally down-regulated gene 8 antikoerper, CG10679 gene product from transcript CG10679-RB antikoerper, Nedd8 antikoerper, ubiquitin-like protein Nedd8 antikoerper, neural precursor cell expressed, developmentally down-regulated 8 L homeolog antikoerper, NEDD8 antikoerper, Nedd8 antikoerper, nedd8 antikoerper, nedd8.L antikoerper
    Gen-ID
    4738
    Pathways
    Ubiquitin Proteasome Pathway
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