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PUMA Antikörper (N-Term)

BBC3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN541428
  • Target Alle PUMA (BBC3) Antikörper anzeigen
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Bindungsspezifität
    • 16
    • 13
    • 9
    • 8
    • 7
    • 6
    • 6
    • 6
    • 6
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 97
    • 40
    • 39
    • 16
    Human
    Wirt
    • 93
    • 7
    • 1
    Kaninchen
    Klonalität
    • 82
    • 19
    Polyklonal
    Konjugat
    • 53
    • 6
    • 5
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PUMA Antikörper ist unkonjugiert
    Applikation
    • 82
    • 34
    • 31
    • 22
    • 17
    • 15
    • 14
    • 13
    • 9
    • 8
    • 5
    • 3
    • 2
    • 2
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit polyclonal antibody raised against synthetic peptide of BBC3.
    Spezifität
    This sequence is identical between a and b forms of the PUMA proteins. K-562 cell lysate can be used as a positive control and a band at approximately 23 KDa can be detected. antibody can also detect PUMA by immunohistochemistry at 10 μg/mL.
    Kreuzreaktivität
    Human
    Immunogen
    A synthetic peptide corresponding to N-terminus 14 amino acids of human BBC3.
    Top Product
    Discover our top product BBC3 Primärantikörper
  • Applikationshinweise
    Western Blot (2-4 μg/mL)
    The optimal working dilution should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In PBS (0.02 % sodium azide)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Yu, Zhang, Hwang, Kinzler, Vogelstein: "PUMA induces the rapid apoptosis of colorectal cancer cells." in: Molecular cell, Vol. 7, Issue 3, pp. 673-82, (2001) (PubMed).

    Nakano, Vousden: "PUMA, a novel proapoptotic gene, is induced by p53." in: Molecular cell, Vol. 7, Issue 3, pp. 683-94, (2001) (PubMed).

    Han, Flemington, Houghton, Gu, Zambetti, Lutz, Zhu, Chittenden: "Expression of bbc3, a pro-apoptotic BH3-only gene, is regulated by diverse cell death and survival signals." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 98, Issue 20, pp. 11318-23, (2001) (PubMed).

  • Target
    PUMA (BBC3) (BCL2 Binding Component 3 (BBC3))
    Andere Bezeichnung
    PUMA (BBC3 Produkte)
    Synonyme
    BBC3 antikoerper, Puma antikoerper, JFY-1 antikoerper, JFY1 antikoerper, PUMA antikoerper, PUMA/JFY1 antikoerper, BCL2 binding component 3 antikoerper, Bcl-2 binding component 3 antikoerper, BBC3 antikoerper, Bbc3 antikoerper, bbc3 antikoerper
    Gen-ID
    27113
    Pathways
    p53 Signalweg, Positive Regulation of Endopeptidase Activity
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