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DIABLO Antikörper (AA 225-239)

DIABLO Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN541409
  • Target Alle DIABLO Antikörper anzeigen
    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
    Bindungsspezifität
    • 10
    • 5
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 225-239
    Reaktivität
    • 61
    • 27
    • 26
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 54
    • 7
    • 1
    Kaninchen
    Klonalität
    • 44
    • 18
    Polyklonal
    Konjugat
    • 37
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser DIABLO Antikörper ist unkonjugiert
    Applikation
    • 35
    • 17
    • 14
    • 11
    • 6
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit polyclonal antibody raised against synthetic peptide of DIABLO.
    Spezifität
    Human heart tissue lysate can be used as positive control and a 25 KDa band can be detected.
    Kreuzreaktivität
    Human, Maus, Ratte
    Immunogen
    A synthetic peptide corresponding to amino acids 225-239 of human DIABLO.
    Top Product
    Discover our top product DIABLO Primärantikörper
  • Applikationshinweise
    Western Blot (0.5-1 μg/mL)
    The optimal working dilution should be determined by the end user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    In PBS (0.02 % sodium azide)
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Store at 4°C for three months. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Du, Fang, Li, Li, Wang: "Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition." in: Cell, Vol. 102, Issue 1, pp. 33-42, (2000) (PubMed).

    Srinivasula, Datta, Fan, Fernandes-Alnemri, Huang, Alnemri: "Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway." in: The Journal of biological chemistry, Vol. 275, Issue 46, pp. 36152-7, (2000) (PubMed).

    Chai, Du, Wu, Kyin, Wang, Shi: "Structural and biochemical basis of apoptotic activation by Smac/DIABLO." in: Nature, Vol. 406, Issue 6798, pp. 855-62, (2000) (PubMed).

  • Target
    DIABLO (Second Mitochondria-Derived Activator of Caspase (DIABLO))
    Andere Bezeichnung
    DIABLO / SMAC (DIABLO Produkte)
    Synonyme
    smac antikoerper, smac3 antikoerper, diablo-s antikoerper, 0610041G12Rik antikoerper, 1700006L01Rik antikoerper, AU040403 antikoerper, Smac antikoerper, DFNA64 antikoerper, SMAC antikoerper, DBO antikoerper, XSmac antikoerper, diablo, IAP-binding mitochondrial protein antikoerper, diablo IAP-binding mitochondrial protein antikoerper, diablo, IAP-binding mitochondrial protein L homeolog antikoerper, diablo antikoerper, Diablo antikoerper, DIABLO antikoerper, diablo.L antikoerper
    Gen-ID
    56616
    Pathways
    Apoptose, Caspase Kaskade in der Apoptose, Positive Regulation of Endopeptidase Activity
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