ABCG1
Reaktivität: Human
WB, ELISA
Wirt: Kaninchen
Polyclonal
unconjugated
Applikationshinweise
Western Blot (1:500) The optimal working dilution should be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In Tris-citrate/phosphate buffer, pH 7.0-8.0 (0.09 % sodium azide)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store at 4°C. Do not freeze.
Burgess, Parkinson, Racke, Hirsch-Reinshagen, Fan, Wong, Stukas, Theroux, Chan, Donkin, Wilkinson, Balik, Christie, Poirier, Lütjohann, Demattos, Wellington: "ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo." in: Journal of lipid research, Vol. 49, Issue 6, pp. 1254-67, (2008) (PubMed).
Delvecchio, Bilan, Nair, Capone: "LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1." in: American journal of physiology. Lung cellular and molecular physiology, Vol. 295, Issue 5, pp. L949-57, (2008) (PubMed).
Tansley, Burgess, Bryan, Su, Hirsch-Reinshagen, Pearce, Chan, Wilkinson, Evans, Naus, McIsaac, Bromley, Song, Yang, Wang, DeMattos, Wellington: "The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein." in: Journal of lipid research, Vol. 48, Issue 5, pp. 1022-34, (2007) (PubMed).
Wang, Kiss, Franklin, McBride, Whitman, Marcel: "Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways." in: Journal of lipid research, Vol. 48, Issue 3, pp. 633-45, (2007) (PubMed).
Ranalletta, Wang, Han, Yvan-Charvet, Welch, Tall: "Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 26, Issue 10, pp. 2308-15, (2006) (PubMed).
Target
ABCG1
(ATP-Binding Cassette, Sub-Family G (WHITE), Member 1 (ABCG1))