INSIG1 Antikörper (AA 1-100)

Produktnummer ABIN540703

Produktdetails anti-INSIG1 Antikörper

Target: INSIG1 (Insulin Induced Gene 1 (INSIG1))

Bindungsspezifität: AA 1-100

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSIG1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of INSIG1.

Spezifität: This antibody is specific to Insig1 but not Insig2.

Kreuzreaktivität: Human

Immunogen: A synthetic peptide corresponding to amino acids 1-100 of human INSIG1.

Anwendungsinformationen

Applikationshinweise: Western Blot (2 μg/mL)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (30 % glycerol, 0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-INSIG1 Antikörper (ABIN540703)

De Marinis, Martini, Trentalance, Pallottini: "Sex differences in hepatic regulation of cholesterol homeostasis." in: The Journal of endocrinology, Vol. 198, Issue 3, pp. 635-43, (2008) (PubMed).

Gong, Lee, Lee, Goldstein, Brown, Ye: "Sterol-regulated ubiquitination and degradation of Insig-1 creates a convergent mechanism for feedback control of cholesterol synthesis and uptake." in: Cell metabolism, Vol. 3, Issue 1, pp. 15-24, (2006) (PubMed).

Engelking, Liang, Hammer, Takaishi, Kuriyama, Evers, Li, Horton, Goldstein, Brown: "Schoenheimer effect explained--feedback regulation of cholesterol synthesis in mice mediated by Insig proteins." in: The Journal of clinical investigation, Vol. 115, Issue 9, pp. 2489-98, (2005) (PubMed).

Details zu INSIG1

Target: INSIG1 (Insulin Induced Gene 1 (INSIG1))

Andere Bezeichnung: INSIG1 (INSIG1 Produkte)

Synonyme: cl-6 antikoerper, cl6 antikoerper, CL-6 antikoerper, CL6 antikoerper, fb55a03 antikoerper, fi35b10 antikoerper, wu:fb55a03 antikoerper, wu:fi35b10 antikoerper, zgc:55439 antikoerper, 1810013C12Rik antikoerper, Insig-1 antikoerper, INSIG-1 antikoerper, insulin induced gene 1 antikoerper, insulin induced gene 1 L homeolog antikoerper, INSIG1 antikoerper, insig1 antikoerper, insig1.L antikoerper, Insig1 antikoerper

Gen-ID: 3638

Pathways: ER-Nucleus Signaling