NPC1 Antikörper (AA 1230-1278)

Produktnummer ABIN540364

Produktdetails anti-NPC1 Antikörper

Target: NPC1 (Niemann-Pick Disease, Type C1 (NPC1))

Bindungsspezifität: AA 1230-1278

Reaktivität: Human, Maus, Hamster

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NPC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunoelectron Microscopy (IEM)

Verwendungszweck: Rabbit polyclonal antibody raised against synthetic peptide of NPC1.

Spezifität: This antibody is specific to NPC1 protein.

Kreuzreaktivität: Hamster, Human, Maus

Immunogen: A synthetic peptide corresponding to amino acids 1230-1278 at C-terminus of human NPC1.

Anwendungsinformationen

Applikationshinweise: Immunofluorescence (1:250)
Western Blot (1:1000-1:3000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-NPC1 Antikörper (ABIN540364)

Burke, Colvin, Myatt, Graf, Schroeder, Woollett: "Transport of maternal cholesterol to the fetus is affected by maternal plasma cholesterol concentrations in the golden Syrian hamster." in: Journal of lipid research, Vol. 50, Issue 6, pp. 1146-55, (2009) (PubMed).

Millard, Srivastava, Traub, Schaffer, Ory: "Niemann-pick type C1 (NPC1) overexpression alters cellular cholesterol homeostasis." in: The Journal of biological chemistry, Vol. 275, Issue 49, pp. 38445-51, (2001) (PubMed).

Frolov, Srivastava, Daphna-Iken, Traub, Schaffer, Ory: "Cholesterol overload promotes morphogenesis of a Niemann-Pick C (NPC)-like compartment independent of inhibition of NPC1 or HE1/NPC2 function." in: The Journal of biological chemistry, Vol. 276, Issue 49, pp. 46414-21, (2001) (PubMed).

Details zu NPC1

Target: NPC1 (Niemann-Pick Disease, Type C1 (NPC1))

Andere Bezeichnung: NPC1 (NPC1 Produkte)

Synonyme: NPC antikoerper, 9130221N23Rik antikoerper, Gm243 antikoerper, Cdig2 antikoerper, im:7149020 antikoerper, wu:fb53a12 antikoerper, wu:fc29a12 antikoerper, A430089E03Rik antikoerper, C85354 antikoerper, D18Ertd139e antikoerper, D18Ertd723e antikoerper, lcsd antikoerper, nmf164 antikoerper, spm antikoerper, NPC intracellular cholesterol transporter 1 antikoerper, NPC1 like intracellular cholesterol transporter 1 antikoerper, Niemann-Pick disease, type C1 antikoerper, Niemann-Pick C1 protein antikoerper, NPC1 antikoerper, Npc1l1 antikoerper, Npc1 antikoerper, npc1 antikoerper, LOC579887 antikoerper

Gen-ID: 4864