BAD Antikörper (BCL2-Associated Agonist of Cell Death) (pSer136)

Details for Product anti-BAD Antibody No. ABIN537568
Antigen
  • bad
  • fa01b12
  • wu:fa01b12
  • wu:fa96d04
  • BAD
  • BBC2
  • BCL2L8
  • AI325008
  • Bbc2
  • BCL2-associated agonist of cell death b
  • BCL2 associated agonist of cell death
  • BCL2-associated agonist of cell death
  • badb
  • BAD
  • Bad
Epitop
pSer136, pSer99
63
58
53
52
46
46
45
37
28
24
24
18
18
18
18
18
18
17
17
17
17
17
17
17
17
17
17
17
17
16
15
14
13
11
10
10
10
10
10
9
8
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
799
476
325
20
17
8
5
4
3
2
2
1
1
1
1
1
Wirt
Kaninchen
989
41
2
1
Klonalität
Polyklonal
Konjugat
Dieser BAD Antikörper ist unkonjugiert
74
66
66
63
62
61
12
12
12
12
12
12
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
546
525
381
336
111
79
37
35
19
19
10
7
5
3
2
1
1
1
1
Optionen
Verwendungszweck Rabbit polyclonal antibody raised against synthetic phosphopeptide of BAD.
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S99 of human BAD.
Plasmids, Primers & others Plasmide, Primers & weitere BAD products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Bcl-2-like 8 (BAD Antibody Abstract)
Pathways MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
Applikations-hinweise Immunohistochemistry (1:50-100)
Dot Blot (1:500)
The optimal working dilution should be determined by the end user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In PBS (0.09 % sodium azide)
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Image no. 1 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer136), (pSer99) antibody (ABIN537568) Formalin-fixed and paraffin-embedded human cancer tissue reacted with BAD (phospho S9...
Produkt verwendet in: Ying, Seiffert, Häcker, Fischer: "Broad degradation of proapoptotic proteins with the conserved Bcl-2 homology domain 3 during infection with Chlamydia trachomatis." in: Infection and immunity, Vol. 73, Issue 3, pp. 1399-403, 2005 (PubMed).

Antignani, Youle: "A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad." in: Biochemistry, Vol. 44, Issue 10, pp. 4074-82, 2005 (PubMed).

Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: "Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells." in: The Journal of biological chemistry, Vol. 280, Issue 20, pp. 19757-67, 2005 (PubMed).

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