BAD Antikörper (BCL2-Associated Agonist of Cell Death) (pSer112)

Details for Product anti-BAD Antibody No. ABIN537567
Antigen
  • bad
  • fa01b12
  • wu:fa01b12
  • wu:fa96d04
  • BAD
  • BBC2
  • BCL2L8
  • AI325008
  • Bbc2
  • BCL2-associated agonist of cell death b
  • BCL2 associated agonist of cell death
  • BCL2-associated agonist of cell death
  • badb
  • BAD
  • Bad
Epitop
pSer112, pSer75
65
57
56
52
46
46
45
40
29
24
24
24
17
17
17
17
17
17
17
16
16
16
16
16
16
16
16
16
16
16
15
14
14
12
10
10
10
9
9
9
9
7
5
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
810
496
347
20
19
8
5
4
3
2
2
1
1
1
1
1
Wirt
Kaninchen
994
42
2
1
Klonalität
Polyklonal
Konjugat
Dieser BAD Antikörper ist unkonjugiert
74
67
67
63
62
61
12
12
12
12
12
12
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
550
531
361
360
107
79
41
33
19
14
10
8
6
3
2
1
1
1
1
Optionen
Verwendungszweck Rabbit polyclonal antibody raised against synthetic phosphopeptide of BAD.
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S75 of human BAD.
Plasmids, Primers & others Plasmide, Primers & weitere BAD products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung Bcl-2-like 8 (BAD Antibody Abstract)
Pathways MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
Applikations-hinweise Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In PBS (0.09 % sodium azide)
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Image no. 1 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112), (pSer75) antibody (ABIN537567) Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted wi...
Image no. 2 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112), (pSer75) antibody (ABIN537567) The BAD (phospho S75) polyclonal antibody is used in Western blot to detect Phospho-...
Produkt verwendet in: Ying, Seiffert, Häcker, Fischer: "Broad degradation of proapoptotic proteins with the conserved Bcl-2 homology domain 3 during infection with Chlamydia trachomatis." in: Infection and immunity, Vol. 73, Issue 3, pp. 1399-403, 2005 (PubMed).

Antignani, Youle: "A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad." in: Biochemistry, Vol. 44, Issue 10, pp. 4074-82, 2005 (PubMed).

Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: "Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells." in: The Journal of biological chemistry, Vol. 280, Issue 20, pp. 19757-67, 2005 (PubMed).

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