BAD Antikörper (BCL2-Associated Agonist of Cell Death) (pSer112)

Details for Product anti-BAD Antibody No. ABIN537567
Antigen
Epitop
pSer112, pSer75
62
58
53
53
46
46
45
38
28
24
24
18
18
18
18
18
18
18
17
17
17
17
17
17
17
17
17
17
17
17
15
14
12
11
10
10
10
10
10
9
7
6
4
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human
796
474
325
20
19
8
5
4
3
2
2
1
1
1
1
1
Wirt
Kaninchen
988
41
2
1
Klonalität
Polyklonal
Konjugat
Dieser BAD Antikörper ist unkonjugiert
74
67
67
63
62
61
12
12
12
12
12
12
6
6
6
6
6
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
Applikation
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
548
522
383
334
109
79
35
35
19
19
8
7
5
3
2
1
1
1
1
Optionen
Verwendungszweck Rabbit polyclonal antibody raised against synthetic phosphopeptide of BAD.
Immunogen Synthetic phosphopeptide (conjugated with KLH) corresponding to residues surrounding S75 of human BAD.
Antigen
Andere Bezeichnung Bcl-2-like 8 (BAD Antibody Abstract)
Pathways MAPK Signalweg, PI3K-Akt Signalweg, RTK Signalweg, Apoptose, Fc-epsilon Rezeptor Signalübertragung, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Positive Regulation of Endopeptidase Activity, Regulation of Carbohydrate Metabolic Process, Hepatitis C, CXCR4-mediated Signaling Events
Applikations-hinweise Western Blot (1:1000)
Immunohistochemistry (1:50-100)
The optimal working dilution should be determined by the end user.
Beschränkungen Nur für Forschungszwecke einsetzbar
Buffer In PBS (0.09 % sodium azide)
Lagerung 4 °C,-20 °C
Informationen zur Lagerung Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Bilder des Herstellers
Image no. 1 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112), (pSer75) antibody (ABIN537567) Formalin-fixed and paraffin-embedded human hepatocellular carcinoma tissue reacted wi...
Image no. 2 for anti-BCL2-Associated Agonist of Cell Death (BAD) (pSer112), (pSer75) antibody (ABIN537567) The BAD (phospho S75) polyclonal antibody is used in Western blot to detect Phospho-...
Produkt verwendet in: Ying, Seiffert, Häcker, Fischer: "Broad degradation of proapoptotic proteins with the conserved Bcl-2 homology domain 3 during infection with Chlamydia trachomatis." in: Infection and immunity, Vol. 73, Issue 3, pp. 1399-403, 2005 (PubMed).

Antignani, Youle: "A chimeric protein induces tumor cell apoptosis by delivering the human Bcl-2 family BH3-only protein Bad." in: Biochemistry, Vol. 44, Issue 10, pp. 4074-82, 2005 (PubMed).

Hurbin, Coll, Dubrez-Daloz, Mari, Auberger, Brambilla, Favrot: "Cooperation of amphiregulin and insulin-like growth factor-1 inhibits Bax- and Bad-mediated apoptosis via a protein kinase C-dependent pathway in non-small cell lung cancer cells." in: The Journal of biological chemistry, Vol. 280, Issue 20, pp. 19757-67, 2005 (PubMed).