CD86 Antikörper (APC)

Produktnummer ABIN536040

Produktdetails anti-CD86 Antikörper (APC)

Target: CD86

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD86 Antikörper ist konjugiert mit APC

Applikation: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)

Verwendungszweck: Mouse monoclonal antibody raised against native CD86.

Spezifität: This antibody reacts with CD86 (B7-2), a 70 KDa type I transmembrane glycoprotein of immunoglobulin supergene family, expressed on professional antigen-presenting cells, such as dendritic cells, macrophages or activated B lymphocytes.

Kreuzreaktivität: Human

Immunogen: Native purified CD86 from human ARH-77 cell.

Klon: BU63

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (10 µL in human blood cells 100 µL in whole blood or 10⁶ cells in a suspension)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.2 % BSA, 0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-CD86 Antikörper (APC) (ABIN536040)

Eri, Kodumudi, Summerlin, Srinivasan: "Suppression of colon inflammation by CD80 blockade: evaluation in two murine models of inflammatory bowel disease." in: Inflammatory bowel diseases, Vol. 14, Issue 4, pp. 458-70, (2008) (PubMed).

Giguère, Bounou, Paquette, Madrenas, Tremblay: "Insertion of host-derived costimulatory molecules CD80 (B7.1) and CD86 (B7.2) into human immunodeficiency virus type 1 affects the virus life cycle." in: Journal of virology, Vol. 78, Issue 12, pp. 6222-32, (2004) (PubMed).

Details zu CD86

Target: CD86

Andere Bezeichnung: CD86 (CD86 Produkte)

Synonyme: B7-2 antikoerper, B7.2 antikoerper, B70 antikoerper, CD28LG2 antikoerper, LAB72 antikoerper, B7 antikoerper, CLS1 antikoerper, Cd28l2 antikoerper, ETC-1 antikoerper, Ly-58 antikoerper, Ly58 antikoerper, MB7 antikoerper, MB7-2 antikoerper, TS/A-2 antikoerper, CD86 molecule antikoerper, CD86 antigen antikoerper, integrin subunit alpha 2b antikoerper, CD86 antikoerper, Cd86 antikoerper, Itga2b antikoerper

Gen-ID: 942

Pathways: T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation