Dieser Integrin Alpha2b Antikörper ist konjugiert mit Biotin
Applikation
Flow Cytometry (FACS)
Verwendungszweck
Mouse monoclonal antibody raised against native ITGA2B.
Spezifität
This antibody reacts with CD41 (GPIIb), a transmembrane glycoprotein (integrin family) composed of two chains GPIIb alpha (heavy chain, 120 KDa) and GPIIb beta (light chain, 23 KDa). CD41 is mainly expressed on platelets and megakaryocytes.
Kreuzreaktivität
Human
Immunogen
Native purified ITGA2B from leukocytes of a patient suffering from a LGL-type leukemia.
Flow Cytometry (1:200) The optimal working dilution should be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In PBS, pH 7.4 (0.09 % sodium azide)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
Store at 4°C. Do not freeze. Aliquot to avoid repeated freezing and thawing.
Zhang, Varas, Stadtfeld, Heck, Faust, Graf: "CD41-YFP mice allow in vivo labeling of megakaryocytic cells and reveal a subset of platelets hyperreactive to thrombin stimulation." in: Experimental hematology, Vol. 35, Issue 3, pp. 490-499, (2007) (PubMed).
Ferkowicz, Starr, Xie, Li, Johnson, Shelley, Morrison, Yoder: "CD41 expression defines the onset of primitive and definitive hematopoiesis in the murine embryo." in: Development (Cambridge, England), Vol. 130, Issue 18, pp. 4393-403, (2003) (PubMed).
Mitjavila-Garcia, Cailleret, Godin, Nogueira, Cohen-Solal, Schiavon, Lecluse, Le Pesteur, Lagrue, Vainchenker: "Expression of CD41 on hematopoietic progenitors derived from embryonic hematopoietic cells." in: Development (Cambridge, England), Vol. 129, Issue 8, pp. 2003-13, (2002) (PubMed).