Spectrin beta Chain, Erythrocyte (SPTB) Antikörper

Produktnummer ABIN534235

Produktdetails

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC)

Verwendungszweck: Mouse monoclonal antibody raised against native SPTB.

Spezifität: This antibody is specific to the 220kD human erythroid beta-spectrin. The protein is also present in the membranes of human skeletal muscle cells. Erythroid spectrins, some other proteins of erythroid cytoskeleton, and the transmembrane protein band 3 are highly specific to erythrocytes and their progenitors. They are more reliable markers for erythroid differentiation than Glycophorin A, the commonly used marker for erythroid differentiation, because Glycophorin A is expressed also in many cell lines otherwise exhibiting mainly megakaryotic charasteristics. Monoclonal antibody to erythroid beta-spectrin is derived from the hybridoma produced by fusion between myeloma cells and Balb/c spleen cells.

Kreuzreaktivität: Human

Produktmerkmale: Antibody Reactive Against Native Purified Protein.

Immunogen: Native purified human SPTB.

Klon: DB2

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (1 % BSA, 0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4°C. Do not freeze.

Referenzen

Auranen, Rapola, Pihko, Haltia, Leivo, Soinila, Virtanen, Kalimo, Anderson, Santavuori, Somer: "Muscle membrane-skeleton protein changes and histopathological characterization of muscle-eye-brain disease." in: Neuromuscular disorders : NMD, Vol. 10, Issue 1, pp. 16-23, (2000) (PubMed).

Antigendetails

Target: Spectrin beta Chain, Erythrocyte (SPTB)

Andere Bezeichnung: Spectrin beta chain (erythrocyte) / SPTB (SPTB Produkte)

Synonyme: AI842465 antikoerper, D330027P03Rik antikoerper, Gm1301 antikoerper, Spnb-1 antikoerper, Spnb1 antikoerper, ja antikoerper, jaundiced antikoerper, mKIAA4219 antikoerper, EL3 antikoerper, HS2 antikoerper, HSPTB1 antikoerper, SPH2 antikoerper, spectrin beta, erythrocytic antikoerper, spectrin, beta, erythrocytic antikoerper, SPTB antikoerper, Sptb antikoerper

Gen-ID: 6710

Pathways: Regulation of Actin Filament Polymerization