MGMT Antikörper

Produktnummer ABIN534106

Produktdetails anti-MGMT Antikörper

Target: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser MGMT Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Mouse monoclonal antibody raised against recombinant MGMT.

Spezifität: This antibody is specific to MGMT.

Kreuzreaktivität: Human

Immunogen: Recombinant protein corresponding to human MGMT.

Klon: MT 23-2

Isotyp: IgG2b

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (1:1000)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:500-1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In buffer containing 0.09 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-MGMT Antikörper (ABIN534106)

Cai, Xu, Cooper, Ferkowicz, Hartwell, Pollok, Kelley: "Mitochondrial targeting of human O6-methylguanine DNA methyltransferase protects against cell killing by chemotherapeutic alkylating agents." in: Cancer research, Vol. 65, Issue 8, pp. 3319-27, (2005) (PubMed).

Zuo, Ai, Ratliff, Suen, Hanna, Brent, Fan: "O6-methylguanine-DNA methyltransferase gene: epigenetic silencing and prognostic value in head and neck squamous cell carcinoma." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 13, Issue 6, pp. 967-75, (2004) (PubMed).

Roth, Xu, Luo, Kelley: "Human-yeast chimeric repair protein protects mammalian cells against alkylating agents: enhancement of MGMT protection." in: Cancer gene therapy, Vol. 10, Issue 8, pp. 603-10, (2003) (PubMed).

Details zu MGMT

Target: MGMT (O6-Methylguanine-DNA-Methyltransferase (MGMT))

Andere Bezeichnung: MGMT (MGMT Produkte)

Synonyme: AGT antikoerper, AI267024 antikoerper, Agat antikoerper, O-6-methylguanine-DNA methyltransferase antikoerper, MGMT antikoerper, Mgmt antikoerper

Gen-ID: 4255

Pathways: DNA Reparatur, Positive Regulation of Response to DNA Damage Stimulus