PRDM1 Antikörper (AA 199-409)

Produktnummer ABIN534050

Produktdetails anti-PRDM1 Antikörper

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Bindungsspezifität: AA 199-409

Reaktivität: Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser PRDM1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF)

Verwendungszweck: Mouse monoclonal antibody raised against partial recombinant Prdm1.

Spezifität: This antibody is specific to the Blimp-1. Recognizes a band ~98 KDa and may recognize one ~80 KDa (the beta form).

Kreuzreaktivität: Human, Maus, Schwein

Immunogen: Recombinant protein corresponding to amino acids 199-409 of mouse Prdm1.

Klon: 3H2-E8

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Flow Cytometry (8 μg/mL, 2*10^6/mL cells)
Immunocytochemistry (1:50-1:100)
Immunofluorescence (1:200)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
Western Blot (1:1000)
The optimal working dilution should be

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: In PBS (0.09 % sodium azide)

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.

Referenzen für anti-PRDM1 Antikörper (ABIN534050)

Robertson, Charatsi, Joyner, Koonce, Morgan, Islam, Paterson, Lejsek, Arnold, Kallies, Nutt, Bikoff: "Blimp1 regulates development of the posterior forelimb, caudal pharyngeal arches, heart and sensory vibrissae in mice." in: Development (Cambridge, England), Vol. 134, Issue 24, pp. 4335-45, (2007) (PubMed).

Severa, Coccia, Fitzgerald: "Toll-like receptor-dependent and -independent viperin gene expression and counter-regulation by PRDI-binding factor-1/BLIMP1." in: The Journal of biological chemistry, Vol. 281, Issue 36, pp. 26188-95, (2006) (PubMed).

Gong, Malek: "Cytokine-dependent Blimp-1 expression in activated T cells inhibits IL-2 production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 1, pp. 242-52, (2006) (PubMed).

Cattoretti, Angelin-Duclos, Shaknovich, Zhou, Wang, Alobeid: "PRDM1/Blimp-1 is expressed in human B-lymphocytes committed to the plasma cell lineage." in: The Journal of pathology, Vol. 206, Issue 1, pp. 76-86, (2005) (PubMed).

Chang, Cattoretti, Calame: "The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development." in: Mechanisms of development, Vol. 117, Issue 1-2, pp. 305-9, (2002) (PubMed).

Details zu PRDM1

Target: PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))

Andere Bezeichnung: PRDM1 / BLIMP1 (PRDM1 Produkte)

Synonyme: GB11750 antikoerper, CG5249 antikoerper, Dmel\\CG5249 antikoerper, blimp-1 antikoerper, dBlimp-1 antikoerper, dBlimp1 antikoerper, Blimp-1 antikoerper, Blimp1 antikoerper, nrd antikoerper, prdm1 antikoerper, ubo antikoerper, wu:fb99c12 antikoerper, zgc:91885 antikoerper, MGC52536 antikoerper, PRDM1 antikoerper, blimp1 antikoerper, xblimp1 antikoerper, prdi-bf1 antikoerper, BLIMP1 antikoerper, PRDI-BF1 antikoerper, ZNFPR1A1 antikoerper, PR/SET domain 1 antikoerper, probable serine/threonine-protein kinase DDB_G0282963 antikoerper, CG5249 gene product from transcript CG5249-RF antikoerper, blimp-1 antikoerper, PR domain containing 1a, with ZNF domain antikoerper, PR domain 1 S homeolog antikoerper, B lymphocyte induced maturation protein 1 antikoerper, PR domain 1 antikoerper, PR domain containing 1, with ZNF domain antikoerper, PRDM1 antikoerper, LOC408295 antikoerper, Blimp-1 antikoerper, CpipJ_CPIJ007425 antikoerper, prdm1a antikoerper, prdm1.S antikoerper, prdm1 antikoerper, Prdm1 antikoerper

Gen-ID: 12142

Pathways: Regulation of Muscle Cell Differentiation