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Progesterone Receptor Antikörper (pSer294)

Name: Progesterone Receptor Antikörper (pSer294)
SKU: ABIN533546
Price: 844.8 EUR
Availability: InStock

PGR Reaktivität: Human, Ratte, Maus, Primate WB, IHC (fro) Wirt: Maus Monoclonal 608 unconjugated

Western blot of whole cell T-47D lysate prepared from cells that had been incubated in the presence of the synthetic progestin agonist R5020 (500 nM) showing specific immunolabeling of the ~90k PGR-A isoform and the ~120 PGR-B isoform of the PGR phosphorylated at Ser294.

1 image

(3 Referenzen)

Produktnummer ABIN533546

Datenblatt (PDF)

Target Alle Progesterone Receptor (PGR) Antikörper anzeigen

Progesterone Receptor (PGR)
Bindungsspezifität
16

16

15

14

12

12

11

10

8

8

8

8

7

7

7

7

6

6

5

5

3

3

3

3

2

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
pSer294
Reaktivität
238

41

37

16

15

8

6

6

5

3

3

2

1

1

1

1
Human, Ratte, Maus, Primate
Wirt
182

58

1

1
Maus
Passende Sekundärantikörper
Klonalität
176

66
Monoklonal
Konjugat
119

21

11

11

8

7

7

7

7

7

7

7

2

2

2

2

2

2

2

2

2

2

2

1
Dieser Progesterone Receptor Antikörper ist unkonjugiert
Applikation
175

90

56

32

28

26

26

24

18

18

17

11

6

3

2

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Verwendungszweck

Mouse monoclonal antibody raised against synthetic phosphopeptide of PGR.

Spezifität

This antibody recognizes ~90KDa PR-A isoform and the ~120 KDa PR-B isoform.

Kreuzreaktivität

Human, Maus, Primate, Ratte

Produktmerkmale

Antibody Reactive Against Synthetic Peptide.

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding S294 of human PGR.

Klon

608

Isotyp

IgG1

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PGR Reaktivität: Human WB, ELISA, IHC (p), IF Wirt: Maus Monoclonal 5D10 unconjugated

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PGR Reaktivität: Human WB, IHC Wirt: Kaninchen Monoclonal unconjugated

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PGR Reaktivität: Human WB, IHC, ELISA, FACS Wirt: Maus Monoclonal 2E4B9 unconjugated

anti-Progesterone Receptor (PGR) antibody
PGR Reaktivität: Human, Ratte, Maus, Affe WB, IHC, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 1-250) antibody
PGR Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 501-600) antibody
PGR Reaktivität: Human WB, ELISA, IHC (p), IHC (fro), IF (cc), IF (p), FACS Wirt: Kaninchen Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (pSer190) antibody
PGR Reaktivität: Human WB, IHC, ELISA, IF Wirt: Kaninchen Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (N-Term) antibody
PGR Reaktivität: Human IHC (p), IF, ICC Wirt: Kaninchen Polyclonal unconjugated

anti-Progesterone Receptor (PGR) (AA 483-571) antibody
PGR Reaktivität: Human IHC, StM Wirt: Maus Monoclonal PGR-2694 unconjugated

Applikationshinweise

Immunohistochemistry (Frozen sections) (1:1000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

In 10 mM HEPES, 150 mM NaCl, pH 7.5 (50 % glycerol, 10 % BSA)

Lagerung

-20 °C

Informationen zur Lagerung

Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
Edwards: "Regulation of signal transduction pathways by estrogen and progesterone." in: Annual review of physiology, Vol. 67, pp. 335-76, (2005) (PubMed).

Lin, Woon, Aw, Guo: "Distinct molecular pathways mediate progesterone-induced growth inhibition and focal adhesion." in: Endocrinology, Vol. 144, Issue 12, pp. 5650-7, (2003) (PubMed).

Clemm, Sherman, Boonyaratanakornkit, Schrader, Weigel, Edwards: "Differential hormone-dependent phosphorylation of progesterone receptor A and B forms revealed by a phosphoserine site-specific monoclonal antibody." in: Molecular endocrinology (Baltimore, Md.), Vol. 14, Issue 1, pp. 52-65, (2000) (PubMed).
Target

Progesterone Receptor (PGR)

Andere Bezeichnung

Progesterone receptor (PGR Produkte)

Synonyme

NR3C3 antikoerper, PR antikoerper, 9930019P03Rik antikoerper, BB114106 antikoerper, ENSMUSG00000074510 antikoerper, PR-A antikoerper, PR-B antikoerper, XPR-1 antikoerper, pgr antikoerper, xpr-2 antikoerper, LOC443444 antikoerper, PGR antikoerper, pg antikoerper, pr antikoerper, gb:dq017620 antikoerper, progesterone receptor antikoerper, progesterone receptor L homeolog antikoerper, PGR antikoerper, Pgr antikoerper, pgr.L antikoerper, pgr antikoerper

Gen-ID

5241

Pathways

Nuclear Receptor Transcription Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Smooth Muscle Cell Migration