The optimal working dilution should be determined by the end user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Buffer
In PBS (0.05 % BSA, 0.05 % sodium azide)
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C,-20 °C
Informationen zur Lagerung
Store at 4°C. For long term storage store at -20°C. Aliquot to avoid repeated freezing and thawing.
Jackson-Bernitsas, Ichikawa, Takada, Myers, Lin, Darnay, Chaturvedi, Aggarwal: "Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma." in: Oncogene, Vol. 26, Issue 10, pp. 1385-97, (2007) (PubMed).
Vunta, Davis, Palempalli, Bhat, Arner, Thompson, Peterson, Reddy, Prabhu: "The anti-inflammatory effects of selenium are mediated through 15-deoxy-Delta12,14-prostaglandin J2 in macrophages." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 17964-73, (2007) (PubMed).
Beraza, Lüdde, Assmus, Roskams, Vander Borght, Trautwein: "Hepatocyte-specific IKK gamma/NEMO expression determines the degree of liver injury." in: Gastroenterology, Vol. 132, Issue 7, pp. 2504-17, (2007) (PubMed).
Lamothe, Webster, Gopinathan, Besse, Campos, Darnay: "TRAF6 ubiquitin ligase is essential for RANKL signaling and osteoclast differentiation." in: Biochemical and biophysical research communications, Vol. 359, Issue 4, pp. 1044-9, (2007) (PubMed).
Sethi, Ahn, Sandur, Lin, Chaturvedi, Aggarwal: "Indirubin enhances tumor necrosis factor-induced apoptosis through modulation of nuclear factor-kappa B signaling pathway." in: The Journal of biological chemistry, Vol. 281, Issue 33, pp. 23425-35, (2006) (PubMed).
Target
IKBKB
(Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase beta (IKBKB))