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LARP6 Antikörper (AA 1-491)

LARP6 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
Produktnummer ABIN527496
  • Target Alle LARP6 Antikörper anzeigen
    LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))
    Bindungsspezifität
    • 8
    • 8
    • 7
    • 5
    • 2
    • 2
    • 1
    • 1
    AA 1-491
    Reaktivität
    • 27
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 26
    • 1
    Maus
    Klonalität
    • 27
    Polyklonal
    Konjugat
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    Dieser LARP6 Antikörper ist unkonjugiert
    Applikation
    • 21
    • 17
    • 14
    • 14
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    Mouse polyclonal antibody raised against a full-length human LARP6 protein.
    Sequenz
    MAQSGGEARP GPKTAVQIRV AIQEAEDVDE LEDEEEGAET RGAGDPARYL SPGWGSASEE EPSRGHSGTT ASGGENERED LEQEWKPPDE ELIKKLVDQI EFYFSDENLE KDAFLLKHVR RNKLGYVSVK LLTSFKKVKH LTRDWRTTAH ALKYSVVLEL NEDHRKVRRT TPVPLFPNEN LPSKMLLVYD LYLSPKLWAL ATPQKNGRVQ EKVMEHLLKL FGTFGVISSV RILKPGRELP PDIRRISSRY SQVGTQECAI VEFEEVEAAI KAHEFMITES QGKENMKAVL IGMKPPKKKP AKDKNHDEEP TASIHLNKSL NKRVEELQYM GDESSANSSS DPESNPTSPM AGRRHAATNK LSPSGHQNLF LSPNASPCTS PWSSPLAQRK GVSRKSPLAE EGRLNCSTSP EIFRKCMDYS SDSSVTPSGS PWVRRRRQAE MGTQEKSPGT SPLLSRKMQT ADGLPVGVLR LPRGPDNTRG FHGHERSRAC V
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    LARP6 (NP_060827, 1 a.a. ~ 491 a.a) full-length human protein.
    Top Product
    Discover our top product LARP6 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Blackstock, Higashi, Sukhanov, Shai, Stefanovic, Tabony, Yoshida, Delafontaine: "Insulin-like growth factor-1 increases synthesis of collagen type I via induction of the mRNA-binding protein LARP6 expression and binding to the 5' stem-loop of COL1a1 and COL1a2 mRNA." in: The Journal of biological chemistry, Vol. 289, Issue 11, pp. 7264-74, (2014) (PubMed).

    Wang, Stefanovic: "Role of LARP6 and nonmuscle myosin in partitioning of collagen mRNAs to the ER membrane." in: PLoS ONE, Vol. 9, Issue 10, pp. e108870, (2014) (PubMed).

    Manojlovic, Blackmon, Stefanovic: "Tacrolimus (FK506) prevents early stages of ethanol induced hepatic fibrosis by targeting LARP6 dependent mechanism of collagen synthesis." in: PLoS ONE, Vol. 8, Issue 6, pp. e65897, (2013) (PubMed).

    Vukmirovic, Manojlovic, Stefanovic: "Serine-threonine kinase receptor-associated protein (STRAP) regulates translation of type I collagen mRNAs." in: Molecular and cellular biology, Vol. 33, Issue 19, pp. 3893-906, (2013) (PubMed).

    Manojlovic, Stefanovic: "A novel role of RNA helicase A in regulation of translation of type I collagen mRNAs." in: RNA (New York, N.Y.), Vol. 18, Issue 2, pp. 321-34, (2012) (PubMed).

    Challa, Stefanovic: "A novel role of vimentin filaments: binding and stabilization of collagen mRNAs." in: Molecular and cellular biology, Vol. 31, Issue 18, pp. 3773-89, (2011) (PubMed).

    Cai, Fritz, Stefanovic, Stefanovic: "Binding of LARP6 to the conserved 5' stem-loop regulates translation of mRNAs encoding type I collagen." in: Journal of molecular biology, Vol. 395, Issue 2, pp. 309-26, (2010) (PubMed).

    Cai, Fritz, Stefanovic, Stefanovic: "Nonmuscle myosin-dependent synthesis of type I collagen." in: Journal of molecular biology, Vol. 401, Issue 4, pp. 564-78, (2010) (PubMed).

  • Target
    LARP6 (La Ribonucleoprotein Domain Family, Member 6 (LARP6))
    Andere Bezeichnung
    LARP6 (LARP6 Produkte)
    Synonyme
    im:7142825 antikoerper, wu:fa55b04 antikoerper, ACHN antikoerper, 5430431G03Rik antikoerper, AI552438 antikoerper, Achn antikoerper, RGD1308414 antikoerper, La ribonucleoprotein domain family, member 6b antikoerper, La ribonucleoprotein domain family member 6 antikoerper, La ribonucleoprotein domain family, member 6 antikoerper, larp6b antikoerper, LARP6 antikoerper, Larp6 antikoerper
    Hintergrund
    Full Gene Name: La ribonucleoprotein domain family, member 6
    Synonyms: ACHN,FLJ11196
    Gen-ID
    55323
    NCBI Accession
    NM_018357
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