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RNF111 Antikörper (AA 1-108)

RNF111 Reaktivität: Human WB, ELISA, IF, RNAi Wirt: Maus Monoclonal 1C4 unconjugated
Produktnummer ABIN527194
  • Target Alle RNF111 Antikörper anzeigen
    RNF111 (Ring Finger Protein 111 (RNF111))
    Bindungsspezifität
    • 15
    • 8
    • 7
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    AA 1-108
    Reaktivität
    • 31
    • 25
    • 16
    Human
    Wirt
    • 43
    • 3
    Maus
    Klonalität
    • 45
    • 1
    Monoklonal
    Konjugat
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF111 Antikörper ist unkonjugiert
    Applikation
    • 23
    • 21
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), ELISA, Immunofluorescence (IF), RNA Interference (RNAi)
    Verwendungszweck
    Mouse monoclonal antibody raised against a partial recombinant RNF111.
    Sequenz
    MSQWTPEYNE LYTLKVDMKS EIPSDAPKTQ ESLKGILLHP EPIGAAKSFP AGVEMINSKV GNEFSHLCDD SQKQEKEMNG NQQEQEKSLV VRKKRKSQQA GPSYVQNC
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody Reactive Against Recombinant Protein.
    Immunogen
    RNF111 (NP_060080, 1 a.a. ~ 108 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
    Klon
    1C4
    Isotyp
    IgG2a
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • van Cuijk, van Belle, Turkyilmaz, Poulsen, Janssens, Theil, Sabatella, Lans, Mailand, Houtsmuller, Vermeulen, Marteijn: "SUMO and ubiquitin-dependent XPC exchange drives nucleotide excision repair." in: Nature communications, Vol. 6, pp. 7499, (2015) (PubMed).

    Ma, Chen, Zhang, Yang, Wang, Yu: "RNF111-dependent neddylation activates DNA damage-induced ubiquitination." in: Molecular cell, Vol. 49, Issue 5, pp. 897-907, (2013) (PubMed).

    Erker, Neyret-Kahn, Seeler, Dejean, Atfi, Levy: "Arkadia, a novel SUMO-targeted ubiquitin ligase involved in PML degradation." in: Molecular and cellular biology, Vol. 33, Issue 11, pp. 2163-77, (2013) (PubMed).

    Poulsen, Hansen, Wagner, van Cuijk, van Belle, Streicher, Wikström, Choudhary, Houtsmuller, Marteijn, Bekker-Jensen, Mailand: "RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response." in: The Journal of cell biology, Vol. 201, Issue 6, pp. 797-807, (2013) (PubMed).

    Javelaud, van Kempen, Alexaki, Le Scolan, Luo, Mauviel: "Efficient TGF-?/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression." in: Molecular cancer, Vol. 10, Issue 1, pp. 2, (2011) (PubMed).

    Koinuma, Shinozaki, Nagano, Ikushima, Horiguchi, Goto, Chano, Saitoh, Imamura, Miyazono, Miyazawa: "RB1CC1 protein positively regulates transforming growth factor-beta signaling through the modulation of Arkadia E3 ubiquitin ligase activity." in: The Journal of biological chemistry, Vol. 286, Issue 37, pp. 32502-12, (2011) (PubMed).

    Nagano, Koinuma, Miyazawa, Miyazono: "Context-dependent regulation of the expression of c-Ski protein by Arkadia in human cancer cells." in: Journal of biochemistry, Vol. 147, Issue 4, pp. 545-54, (2010) (PubMed).

    Nanjundan, Cheng, Zhang, Lahad, Kuo, Schmandt, Smith-McCune, Fishman, Gray, Mills: "Overexpression of SnoN/SkiL, amplified at the 3q26.2 locus, in ovarian cancers: a role in ovarian pathogenesis." in: Molecular oncology, Vol. 2, Issue 2, pp. 164-81, (2009) (PubMed).

    Levy, Howell, Das, Harkin, Episkopou, Hill: "Arkadia activates Smad3/Smad4-dependent transcription by triggering signal-induced SnoN degradation." in: Molecular and cellular biology, Vol. 27, Issue 17, pp. 6068-83, (2007) (PubMed).

  • Target
    RNF111 (Ring Finger Protein 111 (RNF111))
    Andere Bezeichnung
    RNF111 (RNF111 Produkte)
    Synonyme
    ARK antikoerper, Arkadia antikoerper, RNF111 antikoerper, rnf111 antikoerper, ark antikoerper, MGC81253 antikoerper, MGC146379 antikoerper, ring finger protein 111 antikoerper, ring finger 111 antikoerper, RNF111 antikoerper, Rnf111 antikoerper, rnf111-b antikoerper, rnf111 antikoerper
    Hintergrund
    Full Gene Name: ring finger protein 111
    Synonyms: ARK,DKFZp313E0731,DKFZp686H1966,DKFZp761D081,FLJ38008
    Gen-ID
    54778
    NCBI Accession
    NM_017610
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