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RNF8 Antikörper (AA 1-485)

RNF8 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
Produktnummer ABIN522468
  • Target Alle RNF8 Antikörper anzeigen
    RNF8 (Ring Finger Protein 8 (RNF8))
    Bindungsspezifität
    • 9
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 1-485
    Reaktivität
    • 51
    • 27
    • 19
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    • 3
    • 1
    • 1
    Maus
    Klonalität
    • 50
    • 1
    Polyklonal
    Konjugat
    • 22
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser RNF8 Antikörper ist unkonjugiert
    Applikation
    • 51
    • 21
    • 13
    • 8
    • 5
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF)
    Verwendungszweck
    Mouse polyclonal antibody raised against a full-length human RNF8 protein.
    Sequenz
    MGEPGFFVTG DRAGGRSWCL RRVGMSAGWL LLEDGCEVTV GRGFGVTYQL VSKICPLMIS RNHCVLKQNP EGQWTIMDNK SLNGVWLNRA RLEPLRVYSI HQGDYIQLGV PLENKENAEY EYEVTEEDWE TIYPCLSPKN DQMIEKNKEL RTKRKFSLDE LAGPGAEGPS NLKSKINKVS CESGQPVKSQ GKGEVASTPS DNLDPKLTAL EPSKTTGAPI YPGFPKVTEV HHEQKASNSS ASQRSLQMFK VTMSRILRLK IQMQEKHEAV MNVKKQTQKG NSKKVVQMEQ ELQDLQSQLC AEQAQQQARV EQLEKTFQEE EQHLQGLEIA QGEKDLKQQL AQALQEHWAL MEELNRSKKD FEAIIQAKNK ELEQTKEEKE KMQAQKEEVL SHMNDVLENE LQCIICSEYF IEAVTLNCAH SFCSYCINEW MKRKIECPIC RKDIKSKTYS LVLDNCINKM VNNLSSEVKE RRIVLIRERK AKRLF
    Kreuzreaktivität
    Human
    Produktmerkmale
    Antibody reactive against mammalian transfected lysate.
    Immunogen
    RNF8 (NP_003949.1, 1 a.a. ~ 485 a.a) full-length human protein.
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    In 1x PBS, pH 7.4
    Handhabung
    Aliquot to avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Hodge, Ismail, Edwards, Hura, Xiao, Tainer, Hendzel, Glover: "RNF8 E3 Ubiquitin Ligase Stimulates Ubc13 E2 Conjugating Activity That Is Essential for DNA Double Strand Break Signaling and BRCA1 Tumor Suppressor Recruitment." in: The Journal of biological chemistry, Vol. 291, Issue 18, pp. 9396-410, (2016) (PubMed).

    Yang, Deng, Hau, Liu, Lau, Cheung, Huen, Tsao: "Epstein-Barr virus BZLF1 protein impairs accumulation of host DNA damage proteins at damage sites in response to DNA damage." in: Laboratory investigation; a journal of technical methods and pathology, Vol. 95, Issue 8, pp. 937-50, (2015) (PubMed).

    Hau, Deng, Jia, Yang, Tsurumi, Chiang, Huen, Tsao: "Role of ATM in the formation of the replication compartment during lytic replication of Epstein-Barr virus in nasopharyngeal epithelial cells." in: Journal of virology, Vol. 89, Issue 1, pp. 652-68, (2014) (PubMed).

    Morris, Boutell, Keppler, Densham, Weekes, Alamshah, Butler, Galanty, Pangon, Kiuchi, Ng, Solomon: "The SUMO modification pathway is involved in the BRCA1 response to genotoxic stress." in: Nature, Vol. 462, Issue 7275, pp. 886-90, (2009) (PubMed).

  • Target
    RNF8 (Ring Finger Protein 8 (RNF8))
    Andere Bezeichnung
    RNF8 (RNF8 Produkte)
    Synonyme
    hRNF8 antikoerper, 3830404E21Rik antikoerper, AIP37 antikoerper, RNF8 antikoerper, rnf8 antikoerper, fc66f09 antikoerper, wu:fc66f09 antikoerper, zgc:55936 antikoerper, zgc:77313 antikoerper, ring finger protein 8 antikoerper, ring finger protein 8, E3 ubiquitin protein ligase S homeolog antikoerper, ring finger protein 8, E3 ubiquitin protein ligase L homeolog antikoerper, ring finger protein 8, E3 ubiquitin protein ligase antikoerper, RNF8 antikoerper, Rnf8 antikoerper, rnf8.S antikoerper, rnf8.L antikoerper, rnf8 antikoerper
    Hintergrund
    Full Gene Name: ring finger protein 8
    Synonyms: FLJ12013,KIAA0646
    Gen-ID
    9025
    NCBI Accession
    NM_003958
    Pathways
    Production of Molecular Mediator of Immune Response
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