CLEC9A Antikörper (AA 15-218)

Produktnummer ABIN5027446

Produktdetails anti-CLEC9A Antikörper

Target: CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))

Bindungsspezifität: AA 15-218

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CLEC9A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Aufreinigung: Protein G Chromatography

Immunogen: A partial length recombinant protein ( a.a 15-218) of CLEC9A was used as the immunogen for this antibody.

Klon: ABM23H8

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu CLEC9A

Target: CLEC9A (C-Type Lectin Domain Family 9, Member A (CLEC9A))

Andere Bezeichnung: ClEC9A (CLEC9A Produkte)

Synonyme: 9830005G06Rik antikoerper, DNGR-1 antikoerper, DNGR1 antikoerper, UNQ9341 antikoerper, RGD1562513 antikoerper, C-type lectin domain family 9, member a antikoerper, C-type lectin domain containing 9A antikoerper, C-type lectin domain family 9, member A antikoerper, Clec9a antikoerper, CLEC9A antikoerper

Hintergrund: CLEC9A is a C-type lectin receptor involved in the sensing and presentation of antigens derived from necrotic cells. It is expressed on the surface of the mouse and human dendritic cell subsets specialized for the uptake and processing of material from dead cells. CLEC9A is expressed at the cell surface as a glycosylated dimer and can mediate endocytosis, but not phagocytosis. It possesses a cytoplasmic immunoreceptor tyrosine-based activation-like motif that can recruit Syk kinase and can induce proinflammatory cytokine production. CLEC9A provides targeted recruitment of the adaptive immune system during infection and can also be utilized to enhance immune responses generated by vaccines.

Molekulargewicht: 44 kDa

Gen-ID: 283420

UniProt: Q6UXN8