LGALS13 Antikörper

Produktnummer ABIN5026980

Produktdetails anti-LGALS13 Antikörper

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LGALS13 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), Western Blotting (WB)

Aufreinigung: Protein G Chromatography

Immunogen: A full length human Galectin-13 protein was used as the immunogen for this antibody.

Klon: ABM4E42

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: WB: 2-4 μg/mL, IHC: 5 μg/mL

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.05 % BSA, PH 7.4

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.

Details zu LGALS13

Target: LGALS13 (Lectin, Galactoside-Binding, Soluble, 13 (LGALS13))

Andere Bezeichnung: Galectin 13 (LGALS13 Produkte)

Synonyme: GAL13 antikoerper, PLAC8 antikoerper, PP13 antikoerper, Gal-11 antikoerper, Gal-13 antikoerper, Gal11 antikoerper, gal-13 antikoerper, galectin 13 antikoerper, avian beta-defensin 13 antikoerper, LGALS13 antikoerper, AvBD13 antikoerper

Hintergrund: Galectin-13 (Gal-13) is a glycan-binding protein that regulates innate and adaptive immune responses. It is predominantly expressed by the syncytiotrophoblast and released from the placenta into the maternal circulation. It has the ability to induce apoptosis of activated T cells in vitro, and divert and kill T cells as well as macrophages in the maternal decidua. Gal-13 with its anti-inflammatory functions plays a role in regulation of maternal immune system, a lack of gal-13 contribute to an imbalance in inflammation processes in the placenta during pregnancy and therefore influences development of gestational diabetes mellitus (GDM). Gal-13 levels are low in the first trimester of pregnancy that confers a higher risk for developing pre-eclampsia later in pregnancy.

Molekulargewicht: 32 kDa

Gen-ID: 29124

UniProt: Q9UHV8