SORCS2 Antikörper (AA 201-300) (Alexa Fluor 750)

Produktnummer ABIN5010850

Produktdetails anti-SORCS2 Antikörper (Alexa Fluor 750)

Target: SORCS2 (Sortilin-Related VPS10 Domain Containing Receptor 2 (SORCS2))

Bindungsspezifität: AA 201-300

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SORCS2 Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human

Homologie: Mouse,Rat

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SORCS2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu SORCS2

Target: SORCS2 (Sortilin-Related VPS10 Domain Containing Receptor 2 (SORCS2))

Andere Bezeichnung: SORCS2 (SORCS2 Produkte)

Synonyme: SORCS2 antikoerper, N28137 antikoerper, mKIAA1329 antikoerper, sortilin related VPS10 domain containing receptor 2 antikoerper, VPS10 domain-containing receptor SorCS2 antikoerper, sortilin-related VPS10 domain containing receptor 2 antikoerper, SORCS2 antikoerper, LOC100467197 antikoerper, sorcs2 antikoerper, Sorcs2 antikoerper

Hintergrund:

Synonyms: KIAA1329, SORCS 2, Sortilin related VPS10 domain containing receptor 2, VPS10 domain receptor protein, VPS10 domain receptor protein SORCS 2, SORC2_HUMAN.

Background: There are three SorCS genes that have diverse, partially overlapping functions in the central nervous system. In the developing and mature central nervous system, SorCS1, SorCS2 and SorCS3 genes are expressed in a combinatorial, non-overlapping pattern. SorCS proteins show homology to the mosaic receptor SorLA and the neurotensin receptor sortilin, based on a common VPS10 domain, which is the hallmark of the SorCS receptor family. SorCS2 (sortilin-related VPS10 domain containing receptor 2) is a 1,150 amino acid single-pass type I membrane protein that is highly expressed in brain and kidney. Containing six BNR repeats and a single PKD domain, SorCS2 is encoded by a gene that maps to human chromosome 4, which encodes nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.