Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

INTS3 Antikörper (AA 960-998) (Alexa Fluor 750)

INTS3 Reaktivität: Human, Maus, Ratte WB, IF (p) Wirt: Kaninchen Polyclonal Alexa Fluor 750
Produktnummer ABIN5005506
  • Target Alle INTS3 Antikörper anzeigen
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Bindungsspezifität
    • 14
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 960-998
    Reaktivität
    • 28
    • 19
    • 17
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 28
    Kaninchen
    Klonalität
    • 28
    Polyklonal
    Konjugat
    • 11
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser INTS3 Antikörper ist konjugiert mit Alexa Fluor 750
    Applikation
    • 24
    • 12
    • 6
    • 5
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Kreuzreaktivität
    Human, Maus, Ratte
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human INTS3
    Isotyp
    IgG
    Top Product
    Discover our top product INTS3 Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    INTS3 (Integrator Complex Subunit 3 (INTS3))
    Andere Bezeichnung
    INTS3 (INTS3 Produkte)
    Synonyme
    INTS3 antikoerper, Ints3 antikoerper, NV18802 antikoerper, ACYPI009450 antikoerper, DL3335W antikoerper, FCAALL.260 antikoerper, embryo defective 2739 antikoerper, C1orf193 antikoerper, C1orf60 antikoerper, INT3 antikoerper, SOSS-A antikoerper, C77668 antikoerper, RGD1304593 antikoerper, si:dkey-27c15.2 antikoerper, integrator complex subunit 3 antikoerper, integrator complex subunit 3 L homeolog antikoerper, embryo defective 2739 antikoerper, INTS3 antikoerper, ints3.L antikoerper, CpipJ_CPIJ008133 antikoerper, ints3 antikoerper, Ints3 antikoerper, LOC100168776 antikoerper, emb2739 antikoerper
    Hintergrund

    Synonyms: INT3, SOSSA, SOSS-A, C1orf60, C1orf193, Integrator complex subunit 3, SOSS complex subunit A, Sensor of single-strand DNA complex subunit A, Sensor of ssDNA subunit A, INTS3

    Background: Component of the Integrator complex. The Integrator complex is involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. Component of the SOSS complex, a multiprotein complex that functions downstream of the MRN complex to promote DNA repair and G2/M checkpoint. The SOSS complex associates with single-stranded DNA at DNA lesions and influences diverse endpoints in the cellular DNA damage response including cell-cycle checkpoint activation, recombinational repair and maintenance of genomic stability. The SOSS complex is required for efficient homologous recombination-dependent repair of double-strand breaks (DSBs) and ATM-dependent signaling pathways. In the SOSS complex, it is required for the assembly of the complex and for stabilization of the complex at DNA damage sites.

    Gen-ID
    65123
    UniProt
    Q68E01
Sie sind hier:
Kundenservice