Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

NDUFAF2 Antikörper (C-Term)

NDUFAF2 Reaktivität: Human WB, IF, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500282
  • Target Alle NDUFAF2 Antikörper anzeigen
    NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))
    Bindungsspezifität
    • 15
    • 7
    • 6
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    C-Term
    Reaktivität
    • 46
    • 9
    • 7
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 46
    Kaninchen
    Klonalität
    • 46
    Polyklonal
    Konjugat
    • 13
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser NDUFAF2 Antikörper ist unkonjugiert
    Applikation
    • 42
    • 23
    • 16
    • 13
    • 13
    • 6
    • 4
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    Mimitin antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human Mimitin.
    Isotyp
    IgG
    Top Product
    Discover our top product NDUFAF2 Primärantikörper
  • Applikationshinweise
    ELISA. Western blot: 1 - 2 μg/mL. Immunocytochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store the antibody (in aliquots) at -20 °C.
  • Target
    NDUFAF2 (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 2 (NDUFAF2))
    Andere Bezeichnung
    Mimitin (NDUFAF2 Produkte)
    Synonyme
    B17.2L antikoerper, MMTN antikoerper, NDUFA12L antikoerper, mimitin antikoerper, Ndufa12l antikoerper, RGD1560158 antikoerper, NDUFAF2 antikoerper, ndufa12l antikoerper, zgc:101036 antikoerper, 1810058I14Rik antikoerper, C86051 antikoerper, NADH:ubiquinone oxidoreductase complex assembly factor 2 antikoerper, NADH:ubiquinone oxidoreductase complex assembly factor 2 L homeolog antikoerper, NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 antikoerper, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 2 antikoerper, NDUFAF2 antikoerper, Ndufaf2 antikoerper, ndufaf2.L antikoerper, ndufaf2 antikoerper
    Hintergrund
    Mimitin, a small mitochondrial protein, whose transcription is directly stimulated by c-Myc, is highly expressed in 80 % of esophageal squamous cell carcinomas (ESCC). Suppression of Mimitin expression by RNA interference had no effect in cancerous cell lines such as human cervical carcinoma or hepatocarcinoma cell lines, but caused a decrease in cell proliferation in human glioblastoma, embryonic lung fibroblastic cells, and ESCC, suggesting Mimitin may play a special role in these types of cells. Mimitin expression is also regulated by MAPK kinases and IL-1, but not through the NF-kB-related pathway. It will interact with the microtubular protein MAP1S and can affect the activities of caspase-3 and -7 in cells stimulated to develop apoptosis. Other experiments suggest that Mimitin also acts as a molecular chaperone for the assembly of the mitochondrial complex I.Synonyms: B17.2-like, Myc-induced mitochondrial protein, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 2, NDUFA12L, NDUFAF2
    Gen-ID
    91942
    NCBI Accession
    NP_777549
    UniProt
    Q8N183
    Pathways
    SARS-CoV-2 Protein Interaktom
Sie sind hier:
Kundenservice