FAM161B Antikörper (AA 451-560) (Alexa Fluor 750)

Produktnummer ABIN5002382

Produktdetails anti-FAM161B Antikörper (Alexa Fluor 750)

Target: FAM161B (Family with Sequence Similarity 161, Member B (FAM161B))

Bindungsspezifität: AA 451-560

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM161B Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Ratte

Homologie: Human,Mouse,Dog,Cow,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human FAM161B

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu FAM161B

Target: FAM161B (Family with Sequence Similarity 161, Member B (FAM161B))

Andere Bezeichnung: FAM161B (FAM161B Produkte)

Synonyme: C14orf44 antikoerper, c14_5547 antikoerper, 9330169D17 antikoerper, 9830169C18Rik antikoerper, RGD1309058 antikoerper, family with sequence similarity 161 member B antikoerper, family with sequence similarity 161, member B antikoerper, FAM161B antikoerper, Fam161b antikoerper

Hintergrund:

Synonyms: C14orf44, Chromosome 14 open reading frame 44, Family with sequence similarity 161, member B, FLJ31697, Hypothetical protein LOC145483, Protein FAM161B, F161B_HUMAN.

Background: FAM161B is a 647 amino acid protein that belongs to the FAM161 family. The gene that encodes FAM161B consists of approximately 16,413 bases and maps to human chromosome 14q24.3. Housing over 700 genes, chromosome 14 comprises nearly 3.5 % of the human genome. Chromosome 14 encodes the Presenilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer?s disease. The SERPINA1 gene is also located on chromosome 14 and, when defective, leads to the genetic disorder 1-antitrypsin deficiency, which is characterized by severe lung complications and liver dysfunction. An inversion of the long arm of chromosome 14 is thought to be involved in T-cell chronic lymphocytic leukemia (CLL), a cancer that affects T lymphocytes.