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Klra2 Antikörper (C-Term)

Klra2 Reaktivität: Maus, Ratte WB, IHC (p), EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN500130
  • Target Alle Klra2 Antikörper anzeigen
    Klra2 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 2 (Klra2))
    Bindungsspezifität
    C-Term
    Reaktivität
    Maus, Ratte
    Wirt
    • 1
    Kaninchen
    Klonalität
    • 1
    Polyklonal
    Konjugat
    • 1
    Dieser Klra2 Antikörper ist unkonjugiert
    Applikation
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Kreuzreaktivität (Details)
    Species reactivity (tested):Human, mouse
    Aufreinigung
    Peptide affinity chromatography
    Immunogen
    KLRA2 antibody was raised against a 14 amino acid peptide near the carboxy terminus of mouse KLRA2.
    Isotyp
    IgG
  • Applikationshinweise
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    PBS containing 0.02 % sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • Target
    Klra2 (Killer Cell Lectin-Like Receptor, Subfamily A, Member 2 (Klra2))
    Andere Bezeichnung
    KLRA2 (Klra2 Produkte)
    Synonyme
    Klra30 antikoerper, Ly49b antikoerper, Ly49i6 antikoerper, killer cell lectin-like receptor, subfamily A, member 2 antikoerper, Klra2 antikoerper
    Hintergrund
    KLRA2 (also known as Ly49B) is a member of the LY49 family of receptors in Natural Killer (NK) cells that bind to major histocompatibility complex (MHC) class 1. These proteins are classified as either activating or inhibitory receptors based on whether they possess an immunoreceptor tyrosine-based inhibitory motif (ITIM) in their cytoplasmic region (for inhibitory receptors), or an immunoreceptor tyrosine-based activation motif (ITAM) that transmits activating signals resulting in phosphorylation of several substrates. KLRA2 is thought to be an inhibitory receptor and associates with the protein tyrosine phosphatases SHP1, SHP2, and SHIP in transfected cells.Synonyms: Killer cell lectin-like receptor 2, Ly49-b, Ly49b, Lymphocyte antigen 49b, T-cell surface glycoprotein Ly-49B
    UniProt
    Q60660
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