CECR6 Antikörper (Alexa Fluor 750)

Produktnummer ABIN4999876

Produktdetails anti-CECR6 Antikörper (Alexa Fluor 750)

Target: CECR6 (Cat Eye Syndrome Chromosome Region, Candidate 6 (CECR6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CECR6 Antikörper ist konjugiert mit Alexa Fluor 750

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CECR6

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu CECR6

Target: CECR6 (Cat Eye Syndrome Chromosome Region, Candidate 6 (CECR6))

Andere Bezeichnung: CECR6 (CECR6 Produkte)

Synonyme: AW048664 antikoerper, RGD1565302 antikoerper, cat eye syndrome chromosome region, candidate 6 antikoerper, transmembrane protein 121B antikoerper, CECR6 antikoerper, tmem121b antikoerper, TMEM121B antikoerper, Tmem121b antikoerper

Hintergrund:

Synonyms: Cat eye syndrome chromosome region candidate 6, Cat eye syndrome chromosome region candidate 6 homolog human, Cat eye syndrome chromosome region candidate 6 homolog, RGD1565302, AW048664, CECR6_HUMAN.

Background: Adenosine deaminase is an enzyme that is present in most tissues and exists predominantly as a monomer, although in some tissues it is associated with adenosine deaminase-binding protein. Adenosine deaminase degrades extracellular adenosine, which is toxic for lymphocytes. A novel family of growth factors that share sequence similarity to adenosine deaminase has been identified. The cat eye syndrome critical region protein (CECR) family includes CECR1, CECR2, CECR3, CECR4, CECR5, CECR6, CECR7, CECR8 and CECR9. The genes encoding CECR proteins are candidates for Cat Eye Syndrome (CES), a developmental disorder associated with the duplication of a 2 Mb region of 22q11.2. CES is characterized by the combination of coloboma of the iris and anal atresia with fistula, downslanting palpebral fissures, preauricular tags and/or pits, frequent occurrence of heart and renal malformations, and normal or near-normal mental development. CECR family members are widely expressed. Specifically, CECR1 has the highest expression in adult heart, lung, lymphoblasts and placenta. CECR2 is also involved in neurulation and chromatin remodeling. Mutations in the CECR2 gene result in neural tube defects.

Gen-ID: 27439