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DRAXIN Antikörper (AA 251-349) (Alexa Fluor 680)

DRAXIN Reaktivität: Human WB, IF (p), IF (cc) Wirt: Kaninchen Polyclonal Alexa Fluor 680
Produktnummer ABIN4998095
  • Target Alle DRAXIN Antikörper anzeigen
    DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
    Bindungsspezifität
    • 14
    • 3
    • 2
    • 2
    • 1
    • 1
    AA 251-349
    Reaktivität
    • 37
    • 22
    • 21
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Human
    Wirt
    • 36
    • 3
    Kaninchen
    Klonalität
    • 39
    Polyklonal
    Konjugat
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser DRAXIN Antikörper ist konjugiert mit Alexa Fluor 680
    Applikation
    • 39
    • 25
    • 12
    • 9
    • 8
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    Homologie
    Human,Mouse,Rat,Cow,Sheep,Pig,Horse,Chicken,Rabbit
    Aufreinigung
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human C1orf187
    Isotyp
    IgG
    Top Product
    Discover our top product DRAXIN Primärantikörper
  • Applikationshinweise
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Konservierungsmittel
    ProClin
    Vorsichtsmaßnahmen
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Haltbarkeit
    12 months
  • Target
    DRAXIN (Dorsal Inhibitory Axon Guidance Protein (DRAXIN))
    Andere Bezeichnung
    C1orf187 (DRAXIN Produkte)
    Synonyme
    C1orf187 antikoerper, draxin antikoerper, AGPA3119 antikoerper, UNQ3119 antikoerper, neucrin antikoerper, 2610109H07Rik antikoerper, MGC113312 antikoerper, dorsal inhibitory axon guidance protein antikoerper, DRAXIN antikoerper, Draxin antikoerper, draxin antikoerper
    Hintergrund

    Synonyms: AGPA3119, C1orf187, Chromosome 1 open reading frame 187, Dorsal inhibitory axon guidance protein, Dorsal repulsive axon guidance protein, DRAXI_HUMAN, Draxin, FLJ34999, MGC117222, Neucrin, OTTHUMP00000002262, UNQ3119.

    Background: C1orf187, also known as Draxin, Dorsal repulsive axon guidance protein and Neucrin, is a 349 amino acid secreted protein that is required of the development of the spinal cord and forebrain commissures. C1orf187 acts as a chemorepulsive guidance protein and directs commissural axons during development by repelling neurite outgrowth from the spinal cord. During development, C1orf187 modulates neural crest migration by reducing the polarization of these cells, leading to reduced velocity of migration and increased frequency of changing direction, leading to a net decrease in migrational distance. It acts as an antagonist of the Wnt signaling pathway by inhibiting the stabilization of cytosolic _-catenin via its interaction with LRP6. C1orf187 inhibits outgrowth from the olfactory bulb and likely contributes to the formation of the lateral olfactory tract.

    Gen-ID
    374946
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