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STAT4 Antikörper (Internal Region)

STAT4 Reaktivität: Human, Hund, Schwein WB, EIA Wirt: Ziege Polyclonal unconjugated
Produktnummer ABIN499124
  • Target Alle STAT4 Antikörper anzeigen
    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
    Bindungsspezifität
    • 38
    • 11
    • 8
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 613-627, Internal Region
    Reaktivität
    • 93
    • 58
    • 36
    • 5
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Human, Hund, Schwein
    Wirt
    • 96
    • 12
    • 2
    • 2
    Ziege
    Klonalität
    • 87
    • 25
    Polyklonal
    Konjugat
    • 57
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser STAT4 Antikörper ist unkonjugiert
    Applikation
    • 81
    • 48
    • 41
    • 24
    • 23
    • 16
    • 13
    • 13
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Sequenz
    C-DHSESGEVRF HSVEP
    Spezifität
    Recognizes STAT4 (aa 613-627).
    Kreuzreaktivität (Details)
    Species reactivity (expected):Canine, Pig.
    Species reactivity (tested):Human.
    Aufreinigung
    Ammonium Sulphate Precipitation followed by Antigen Affinity Chromatography using the immunizing peptide.
    Immunogen
    Peptide with sequence from the internal region (aa 613-627) of the protein sequence according to Human STAT4 (NP_003142.1.) Genename: STAT4
    Top Product
    Discover our top product STAT4 Primärantikörper
  • Applikationshinweise
    Peptide ELISA: Limit Dilution: 1/32000. Western blot: 0.2-0.5 μg/mL. This antibody detects a band of approx. 85 kDa in transfectedHEK293 transiently expressing full-length Human STAT4 (MYC and DYKDDDDK tagged). No bands were observed in mock-transfected HEK293 and the same band was observedusing anti-myc tag antibody.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    0.5 mg/mL
    Buffer
    Tris saline, pH 7.3 containing 0.02 % Sodium Azide as preservative and 0.5 % BSA as stabilizer.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    STAT4 (Signal Transducer and Activator of Transcription 4 (STAT4))
    Andere Bezeichnung
    STAT4 (STAT4 Produkte)
    Synonyme
    SLEB11 antikoerper, signal transducer and activator of transcription 4 antikoerper, STAT4 antikoerper, stat4 antikoerper, Stat4 antikoerper
    Hintergrund
    The STAT 4 protein is a transcription factor activated by hormone and cytokines. STAT 4 is most similar to STAT 1 (52 % ) and STAT 3 (47 %). Functionally STAT 4 is similar to other STAT family members in that it can be tyrosine phosphorylated by JAK 1 or JAK 2. STAT 4 forms homodimers and heterodimers with related STAT family members. Tyrosine phosphorylated STAT 4 can bind the interferon g activated site (GAS), and serine phosphorylation is also required for maximal transcriptional activity. STAT 4 expression is restricted to the thymus, spleen, and testis.Synonyms: Signal transducer and activator of transcription 4
    Gen-ID
    6775
    NCBI Accession
    NP_003142
    UniProt
    Q14765
    Pathways
    JAK-STAT Signalweg
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