GRIN2D Antikörper

Produktnummer ABIN499079

Produktdetails anti-GRIN2D Antikörper

Target: GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIN2D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of NMDAε4 protein. (region surrounding Pro706)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: Western blot: 1: 500 - 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GRIN2D

Target: GRIN2D (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2D (GRIN2D))

Andere Bezeichnung: NMDAR2D (GRIN2D Produkte)

Synonyme: nr2d antikoerper, EB11 antikoerper, GluN2D antikoerper, NMDAR2D antikoerper, NR2D antikoerper, glutamate ionotropic receptor NMDA type subunit 2D antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2D antikoerper, glutamate receptor, ionotropic, N-methyl D-aspartate 2D L homeolog antikoerper, glutamate receptor, ionotropic, NMDA2D (epsilon 4) antikoerper, GRIN2D antikoerper, grin2d.L antikoerper, grin2d antikoerper, Grin2d antikoerper

Hintergrund: Glutamate receptors mediate most excitatory neurotransmission in the brain and play an important role in neural plasticity, neural development and neurodegeneration . Ionotropic glutamate receptors are categorized into NMDA receptors and kainate/AMPA receptors, both of which contain glutamate-gated, caution-specific ion channels . Kainate/AMPA receptors are co-localized with NMDA receptors in many synapses and consist of seven structurally related subunits designated GluR-1 to -7 . The kainate/AMPA receptors are primarily responsible for the fast excitatory neurotransmission by glutamate whereas the NMDA receptors are functionally characterized by a slow kinetic and a high permeability for Ca2+ ions . The NMDA receptors consist of five subunits: epsilion 1, 2, 3, 4 and one zeta subunit . The zeta subunit is expressed throughout the brainstem, whereas the four epsilon subunits display limited distribution.Synonyms: GRIN2D, Glutamate [NMDA] receptor subunit epsilon-4, N-methyl D-aspartate receptor subtype 2D, NMDAR2D, NR2D

Molekulargewicht: approx. 170 kDa

Gen-ID: 2906

NCBI Accession: NP_000827

UniProt: O15399

Pathways: Synaptic Membrane